Prophylactic Dexamethasone for improving perinatal outcome before elective caesarean section at term pregnancy
Background and objectives: With the increase in the incidence of elective caesarean section, and the absence of onset of labour, the increase in the rate of neonatal respiratory morbidities and admissions to neonatal intensive care unit have also been observed. The objective of the study is to eval...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Kurdistan Higher Council Of Medical Specialties
2023-05-01
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| Series: | Advanced Medical Journal |
| Subjects: | |
| Online Access: | https://amj.khcms.edu.krd/index.php/main/article/view/223 |
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| Summary: | Background and objectives: With the increase in the incidence of elective caesarean section, and the absence of onset of labour, the increase in the rate of neonatal respiratory morbidities and admissions to neonatal intensive care unit have also been observed. The objective of the study is to evaluate the role of prophylactic dexamethasone in reducing the occurrence of neonatal respiratory morbidities in term pregnancies before elective caesarean section.
Methods: The study was a prospective cohort study conducted at Maternity Teaching Hospital at Erbil – Iraq from first Septem- ber 2017 till first of September 2018, 400 term pregnant ladies scheduled for elective caesarean section divided to 200 women who received prophylactic 4 doses of 6 mg dexamethasone, and 200 women who received nothing. We compare the incidence of admissions to neonatal intensive care unit, respiratory distress syndrome, transient tachypnea of newborn and early neonatal death between the two groups.
Results: Dexamethasone group showed lower incidences of admissions to neonatal intensive care unit 3.5 % and transient tachypnea of newborn 2.5% than control group 10.5% and 7 % respectively with statistically significant differences between them, using Chi-square test. Respiratory distress syndrome and an early neonatal death have lower incidences in dexamethasone group 2.5% and 0% than control group 3.5% and 1% respectively, but statistically were not significant.
Conclusions: The use of prophylactic antenatal corticosteroid was found significantly to reduce neonatal respiratory morbidities and admissions to neonatal intensive care unit, especially in our center with low neonatal intensive care unit facilities.
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| ISSN: | 2958-8979 2957-3580 |