Association between weight-adjusted waist index and depression in adults with diabetes: a cross-sectional study
Abstract Background The weight-adjusted waist index (WWI) is a new way to measure central obesity, reflecting body fat distribution more effectively. The association between WWI and depression in individuals with diabetes is still not well understood. This study explores this association in diabetic...
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BMC
2025-08-01
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| Series: | BMC Psychiatry |
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| Online Access: | https://doi.org/10.1186/s12888-025-07153-z |
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| author | Mingfeng Ye Jizhao Yao Huanliang Huang Dexiong Chen |
| author_facet | Mingfeng Ye Jizhao Yao Huanliang Huang Dexiong Chen |
| author_sort | Mingfeng Ye |
| collection | DOAJ |
| description | Abstract Background The weight-adjusted waist index (WWI) is a new way to measure central obesity, reflecting body fat distribution more effectively. The association between WWI and depression in individuals with diabetes is still not well understood. This study explores this association in diabetic patients. Methods This study involved adult participants diagnosed with diabetes mellitus in NHANES 2009–2018. We explored the association between WWI and depression through multivariate logistic regression analysis, subgroup analyses, interaction tests, and smoothed curve-fitting methods. Results In Model 3, this study found a significant positive association between WWI and depression among patients with diabetes (OR = 1.38, 95% CI: 1.17–1.63). In the smoothed curve fitting analysis, a nonlinear relationship between WWI and depression was observed, with an inflection point at 12.31. Subgroup analysis indicated that this association was influenced by the poverty income ratio (PIR), with a stronger association observed among diabetic patients with PIR ≥ 1, < 3, and PIR ≥ 3. Conclusions Among patients with diabetes, WWI was significantly positively associated with the prevalence of depression. This association was more pronounced among diabetic patients with PIR ≥ 1, < 3, and PIR ≥ 3. These findings suggest that WWI may be a relevant factor for physicians to consider when assessing depressive symptoms in patients with diabetes. |
| format | Article |
| id | doaj-art-45d65c1eed204d60a7198e7a2f7ad8a8 |
| institution | Kabale University |
| issn | 1471-244X |
| language | English |
| publishDate | 2025-08-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Psychiatry |
| spelling | doaj-art-45d65c1eed204d60a7198e7a2f7ad8a82025-08-24T11:42:50ZengBMCBMC Psychiatry1471-244X2025-08-012511910.1186/s12888-025-07153-zAssociation between weight-adjusted waist index and depression in adults with diabetes: a cross-sectional studyMingfeng Ye0Jizhao Yao1Huanliang Huang2Dexiong Chen3Department of General Medicine, Guangdong Provincial Key Laboratory of Major Obstetric Diseases, Guangdong Provincial Clinical Research Center for Obstetrics and Gynecology, The Third Affiliated Hospital of Guangzhou Medical UniversityDepartment of Dermatology, Guangdong Provincial Key Laboratory of Major Obstetric Diseases, Guangdong Provincial Clinical Research Center for Obstetrics and Gynecology, The Third Affiliated Hospital of Guangzhou Medical UniversityDepartment of General Medicine, Guangdong Provincial Key Laboratory of Major Obstetric Diseases, Guangdong Provincial Clinical Research Center for Obstetrics and Gynecology, The Third Affiliated Hospital of Guangzhou Medical UniversityDepartment of General Medicine, Guangdong Provincial Key Laboratory of Major Obstetric Diseases, Guangdong Provincial Clinical Research Center for Obstetrics and Gynecology, The Third Affiliated Hospital of Guangzhou Medical UniversityAbstract Background The weight-adjusted waist index (WWI) is a new way to measure central obesity, reflecting body fat distribution more effectively. The association between WWI and depression in individuals with diabetes is still not well understood. This study explores this association in diabetic patients. Methods This study involved adult participants diagnosed with diabetes mellitus in NHANES 2009–2018. We explored the association between WWI and depression through multivariate logistic regression analysis, subgroup analyses, interaction tests, and smoothed curve-fitting methods. Results In Model 3, this study found a significant positive association between WWI and depression among patients with diabetes (OR = 1.38, 95% CI: 1.17–1.63). In the smoothed curve fitting analysis, a nonlinear relationship between WWI and depression was observed, with an inflection point at 12.31. Subgroup analysis indicated that this association was influenced by the poverty income ratio (PIR), with a stronger association observed among diabetic patients with PIR ≥ 1, < 3, and PIR ≥ 3. Conclusions Among patients with diabetes, WWI was significantly positively associated with the prevalence of depression. This association was more pronounced among diabetic patients with PIR ≥ 1, < 3, and PIR ≥ 3. These findings suggest that WWI may be a relevant factor for physicians to consider when assessing depressive symptoms in patients with diabetes.https://doi.org/10.1186/s12888-025-07153-zWeight-adjusted waist indexObesityDepressionDiabetesNHANES |
| spellingShingle | Mingfeng Ye Jizhao Yao Huanliang Huang Dexiong Chen Association between weight-adjusted waist index and depression in adults with diabetes: a cross-sectional study BMC Psychiatry Weight-adjusted waist index Obesity Depression Diabetes NHANES |
| title | Association between weight-adjusted waist index and depression in adults with diabetes: a cross-sectional study |
| title_full | Association between weight-adjusted waist index and depression in adults with diabetes: a cross-sectional study |
| title_fullStr | Association between weight-adjusted waist index and depression in adults with diabetes: a cross-sectional study |
| title_full_unstemmed | Association between weight-adjusted waist index and depression in adults with diabetes: a cross-sectional study |
| title_short | Association between weight-adjusted waist index and depression in adults with diabetes: a cross-sectional study |
| title_sort | association between weight adjusted waist index and depression in adults with diabetes a cross sectional study |
| topic | Weight-adjusted waist index Obesity Depression Diabetes NHANES |
| url | https://doi.org/10.1186/s12888-025-07153-z |
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