ANTIFUNGAL PROPHYLAXIS IN IMMUNOCOMPROMISED PATIENTS
Invasive fungal infections (IFIs) represent significant complications in patients with hematological malignancies. Chemoprevention of IFIs may be important in this setting, but most antifungal drugs have demonstrated poor efficacy, particularly in the prevention of invasive aspergillosis. Antifungal...
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| Format: | Article |
| Language: | English |
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PAGEPress Publications
2016-09-01
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| Series: | Mediterranean Journal of Hematology and Infectious Diseases |
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| Online Access: | http://www.mjhid.org/index.php/mjhid/article/view/2609 |
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| author | Lourdes Vazquez |
| author_facet | Lourdes Vazquez |
| author_sort | Lourdes Vazquez |
| collection | DOAJ |
| description | Invasive fungal infections (IFIs) represent significant complications in patients with hematological malignancies. Chemoprevention of IFIs may be important in this setting, but most antifungal drugs have demonstrated poor efficacy, particularly in the prevention of invasive aspergillosis. Antifungal prophylaxis in hematological patients is currently regarded as the gold standard in situations with a high risk of infection, such as acute leukemia, myelodysplastic syndromes, and autologous or allogeneic hematopoietic stem cell transplantation. Over the years, various scientific societies have established a series of recommendations for antifungal prophylaxis based on prospective studies performed with different drugs. However, the prescription of each agent must be personalized, adapting its administration to the characteristics of individual patients and taking into account possible interactions with concomitant medication. |
| format | Article |
| id | doaj-art-45d4ad1c686d45adba773325e8efd8e8 |
| institution | Kabale University |
| issn | 2035-3006 |
| language | English |
| publishDate | 2016-09-01 |
| publisher | PAGEPress Publications |
| record_format | Article |
| series | Mediterranean Journal of Hematology and Infectious Diseases |
| spelling | doaj-art-45d4ad1c686d45adba773325e8efd8e82025-01-02T11:12:29ZengPAGEPress PublicationsMediterranean Journal of Hematology and Infectious Diseases2035-30062016-09-0180e2016040e201604010.4084/mjhid.2016.0401633ANTIFUNGAL PROPHYLAXIS IN IMMUNOCOMPROMISED PATIENTSLourdes Vazquez0Hospital University of Salamanca (Salamanca, Spain). Corresponding author: Lourdes Vazquez, MD Hematology Department, Hospital University of Salamanca, Paseo de San Vicente 58-182, Salamanca, Spain. Tel: ++34 606 195327 E-mail: lvazlo@usal.esInvasive fungal infections (IFIs) represent significant complications in patients with hematological malignancies. Chemoprevention of IFIs may be important in this setting, but most antifungal drugs have demonstrated poor efficacy, particularly in the prevention of invasive aspergillosis. Antifungal prophylaxis in hematological patients is currently regarded as the gold standard in situations with a high risk of infection, such as acute leukemia, myelodysplastic syndromes, and autologous or allogeneic hematopoietic stem cell transplantation. Over the years, various scientific societies have established a series of recommendations for antifungal prophylaxis based on prospective studies performed with different drugs. However, the prescription of each agent must be personalized, adapting its administration to the characteristics of individual patients and taking into account possible interactions with concomitant medication.http://www.mjhid.org/index.php/mjhid/article/view/2609hematopoietic stem cell transplantationImunocompromised patientsFungal infectionsAntifungal prophylaxis |
| spellingShingle | Lourdes Vazquez ANTIFUNGAL PROPHYLAXIS IN IMMUNOCOMPROMISED PATIENTS Mediterranean Journal of Hematology and Infectious Diseases hematopoietic stem cell transplantation Imunocompromised patients Fungal infections Antifungal prophylaxis |
| title | ANTIFUNGAL PROPHYLAXIS IN IMMUNOCOMPROMISED PATIENTS |
| title_full | ANTIFUNGAL PROPHYLAXIS IN IMMUNOCOMPROMISED PATIENTS |
| title_fullStr | ANTIFUNGAL PROPHYLAXIS IN IMMUNOCOMPROMISED PATIENTS |
| title_full_unstemmed | ANTIFUNGAL PROPHYLAXIS IN IMMUNOCOMPROMISED PATIENTS |
| title_short | ANTIFUNGAL PROPHYLAXIS IN IMMUNOCOMPROMISED PATIENTS |
| title_sort | antifungal prophylaxis in immunocompromised patients |
| topic | hematopoietic stem cell transplantation Imunocompromised patients Fungal infections Antifungal prophylaxis |
| url | http://www.mjhid.org/index.php/mjhid/article/view/2609 |
| work_keys_str_mv | AT lourdesvazquez antifungalprophylaxisinimmunocompromisedpatients |