Meeting Report: High-Throughput Technologies for In Vivo Imaging Agents
Combinatorial chemistry and high-throughput screening have become standard tools for discovering new drug candidates with suitable pharmacological properties. Now, those same technologies are starting to be applied to the problem of discovering novel in vivo imaging agents. Important differences in...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2005-04-01
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| Series: | Molecular Imaging |
| Online Access: | https://doi.org/10.1162/15353500200505115 |
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| _version_ | 1850087565835632640 |
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| author | Robert J. Gillies John M. Hoffman Kit S. Lam Anne E. Menkens David R. Piwnica-Worms Daniel C. Sullivan Ralph Weissleder |
| author_facet | Robert J. Gillies John M. Hoffman Kit S. Lam Anne E. Menkens David R. Piwnica-Worms Daniel C. Sullivan Ralph Weissleder |
| author_sort | Robert J. Gillies |
| collection | DOAJ |
| description | Combinatorial chemistry and high-throughput screening have become standard tools for discovering new drug candidates with suitable pharmacological properties. Now, those same technologies are starting to be applied to the problem of discovering novel in vivo imaging agents. Important differences in the biological and pharmacological properties needed for imaging agents, compared to those for a therapeutic agent, require new screening methods that emphasize those characteristics, such as optimized residence time and tissue specificity, that make for a good imaging agent candidate. |
| format | Article |
| id | doaj-art-45c9ed255d7047c5844fbcd5792da747 |
| institution | DOAJ |
| issn | 1536-0121 |
| language | English |
| publishDate | 2005-04-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Molecular Imaging |
| spelling | doaj-art-45c9ed255d7047c5844fbcd5792da7472025-08-20T02:43:12ZengSAGE PublishingMolecular Imaging1536-01212005-04-01410.1162/1535350020050511510.1162_15353500200505115Meeting Report: High-Throughput Technologies for In Vivo Imaging AgentsRobert J. Gillies0John M. Hoffman1Kit S. Lam2Anne E. Menkens3David R. Piwnica-Worms4Daniel C. Sullivan5Ralph Weissleder6University of ArizonaNational Cancer InstituteUniversity of California—DavisNational Cancer InstituteWashington UniversityNational Cancer InstituteHarvard UniversityCombinatorial chemistry and high-throughput screening have become standard tools for discovering new drug candidates with suitable pharmacological properties. Now, those same technologies are starting to be applied to the problem of discovering novel in vivo imaging agents. Important differences in the biological and pharmacological properties needed for imaging agents, compared to those for a therapeutic agent, require new screening methods that emphasize those characteristics, such as optimized residence time and tissue specificity, that make for a good imaging agent candidate.https://doi.org/10.1162/15353500200505115 |
| spellingShingle | Robert J. Gillies John M. Hoffman Kit S. Lam Anne E. Menkens David R. Piwnica-Worms Daniel C. Sullivan Ralph Weissleder Meeting Report: High-Throughput Technologies for In Vivo Imaging Agents Molecular Imaging |
| title | Meeting Report: High-Throughput Technologies for In Vivo Imaging Agents |
| title_full | Meeting Report: High-Throughput Technologies for In Vivo Imaging Agents |
| title_fullStr | Meeting Report: High-Throughput Technologies for In Vivo Imaging Agents |
| title_full_unstemmed | Meeting Report: High-Throughput Technologies for In Vivo Imaging Agents |
| title_short | Meeting Report: High-Throughput Technologies for In Vivo Imaging Agents |
| title_sort | meeting report high throughput technologies for in vivo imaging agents |
| url | https://doi.org/10.1162/15353500200505115 |
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