A Diagnostic Dilemma of Antiglutamic Acid Decarboxylase 65 (Anti-GAD 65) and Mycoplasma Pneumoniae Antibodies in a Girl Presenting with Acute-Onset Obsessive-Compulsive Disorder

Acute-onset obsessive-compulsive disorder can be challenging, especially when triggered by an underlying disease process. Clinicians often turn to Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections (PANDAS), but it is important to consider a broad differential i...

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Main Authors: Cecilia G. Freeman, Antanoid J. Langeveldt, Robyn R. Miller
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Case Reports in Psychiatry
Online Access:http://dx.doi.org/10.1155/2021/6672028
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author Cecilia G. Freeman
Antanoid J. Langeveldt
Robyn R. Miller
author_facet Cecilia G. Freeman
Antanoid J. Langeveldt
Robyn R. Miller
author_sort Cecilia G. Freeman
collection DOAJ
description Acute-onset obsessive-compulsive disorder can be challenging, especially when triggered by an underlying disease process. Clinicians often turn to Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections (PANDAS), but it is important to consider a broad differential in these patients. We present a case of a 9-year-old girl with acute-onset obsessive-compulsive behavior likely triggered by a post-infectious phenomenon that ultimately resolved following treatment with plasmapheresis.
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spelling doaj-art-45c754e05f414c32beb531260f2f79a32025-08-20T03:36:10ZengWileyCase Reports in Psychiatry2090-682X2090-68382021-01-01202110.1155/2021/66720286672028A Diagnostic Dilemma of Antiglutamic Acid Decarboxylase 65 (Anti-GAD 65) and Mycoplasma Pneumoniae Antibodies in a Girl Presenting with Acute-Onset Obsessive-Compulsive DisorderCecilia G. Freeman0Antanoid J. Langeveldt1Robyn R. Miller2Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USADepartment of Pediatrics, Nemours/Alfred I. duPont Hospital for Children, Wilmington, DE, USADepartment of Pediatrics, Nemours/Alfred I. duPont Hospital for Children, Wilmington, DE, USAAcute-onset obsessive-compulsive disorder can be challenging, especially when triggered by an underlying disease process. Clinicians often turn to Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections (PANDAS), but it is important to consider a broad differential in these patients. We present a case of a 9-year-old girl with acute-onset obsessive-compulsive behavior likely triggered by a post-infectious phenomenon that ultimately resolved following treatment with plasmapheresis.http://dx.doi.org/10.1155/2021/6672028
spellingShingle Cecilia G. Freeman
Antanoid J. Langeveldt
Robyn R. Miller
A Diagnostic Dilemma of Antiglutamic Acid Decarboxylase 65 (Anti-GAD 65) and Mycoplasma Pneumoniae Antibodies in a Girl Presenting with Acute-Onset Obsessive-Compulsive Disorder
Case Reports in Psychiatry
title A Diagnostic Dilemma of Antiglutamic Acid Decarboxylase 65 (Anti-GAD 65) and Mycoplasma Pneumoniae Antibodies in a Girl Presenting with Acute-Onset Obsessive-Compulsive Disorder
title_full A Diagnostic Dilemma of Antiglutamic Acid Decarboxylase 65 (Anti-GAD 65) and Mycoplasma Pneumoniae Antibodies in a Girl Presenting with Acute-Onset Obsessive-Compulsive Disorder
title_fullStr A Diagnostic Dilemma of Antiglutamic Acid Decarboxylase 65 (Anti-GAD 65) and Mycoplasma Pneumoniae Antibodies in a Girl Presenting with Acute-Onset Obsessive-Compulsive Disorder
title_full_unstemmed A Diagnostic Dilemma of Antiglutamic Acid Decarboxylase 65 (Anti-GAD 65) and Mycoplasma Pneumoniae Antibodies in a Girl Presenting with Acute-Onset Obsessive-Compulsive Disorder
title_short A Diagnostic Dilemma of Antiglutamic Acid Decarboxylase 65 (Anti-GAD 65) and Mycoplasma Pneumoniae Antibodies in a Girl Presenting with Acute-Onset Obsessive-Compulsive Disorder
title_sort diagnostic dilemma of antiglutamic acid decarboxylase 65 anti gad 65 and mycoplasma pneumoniae antibodies in a girl presenting with acute onset obsessive compulsive disorder
url http://dx.doi.org/10.1155/2021/6672028
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