Clinical role of increased apolipoprotein B levels in coronary heart disease
Aim. To investigate clinical role of serum apolipoprotein B (apo B) levels in coronary heart disease (CHD). Material and methods. The study included 122 patients (mean age 49,7±7,1 years) with possible CHD diagnosis, who underwent clinical and instrumental examination. The diagnosis was confirmed by...
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| Format: | Article |
| Language: | Russian |
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«SILICEA-POLIGRAF» LLC
1970-01-01
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| Series: | Кардиоваскулярная терапия и профилактика |
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| Online Access: | https://cardiovascular.elpub.ru/jour/article/view/1478 |
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| author | S. A. Pataraya D. V. Preobrazhensky |
| author_facet | S. A. Pataraya D. V. Preobrazhensky |
| author_sort | S. A. Pataraya |
| collection | DOAJ |
| description | Aim. To investigate clinical role of serum apolipoprotein B (apo B) levels in coronary heart disease (CHD). Material and methods. The study included 122 patients (mean age 49,7±7,1 years) with possible CHD diagnosis, who underwent clinical and instrumental examination. The diagnosis was confirmed by anamnesis data, stress tests and coronary angiography results. Apo B concentration was measured by immune-enzyme method. Results. In women, sensitivity of elevated apo B levels was lower than that of hypercholesterolemia (HCH); nevertheless, specificity of both parameters was similar. In men, HCH was more sensitive and specific than increased apo B levels. Conclusion. Substantial differences in sensitivity and specificity of increased apo B levels were observed in women and men with possible CHD, as well as in various groups of men. |
| format | Article |
| id | doaj-art-45c485a4151c4c6db0d4f04242cbca0f |
| institution | DOAJ |
| issn | 1728-8800 2619-0125 |
| language | Russian |
| publishDate | 1970-01-01 |
| publisher | «SILICEA-POLIGRAF» LLC |
| record_format | Article |
| series | Кардиоваскулярная терапия и профилактика |
| spelling | doaj-art-45c485a4151c4c6db0d4f04242cbca0f2025-08-20T02:55:48Zrus«SILICEA-POLIGRAF» LLCКардиоваскулярная терапия и профилактика1728-88002619-01251970-01-017751541196Clinical role of increased apolipoprotein B levels in coronary heart diseaseS. A. Pataraya0D. V. Preobrazhensky1Educational and Research Medical Center, RF President Administration, MoscowEducational and Research Medical Center, RF President Administration, MoscowAim. To investigate clinical role of serum apolipoprotein B (apo B) levels in coronary heart disease (CHD). Material and methods. The study included 122 patients (mean age 49,7±7,1 years) with possible CHD diagnosis, who underwent clinical and instrumental examination. The diagnosis was confirmed by anamnesis data, stress tests and coronary angiography results. Apo B concentration was measured by immune-enzyme method. Results. In women, sensitivity of elevated apo B levels was lower than that of hypercholesterolemia (HCH); nevertheless, specificity of both parameters was similar. In men, HCH was more sensitive and specific than increased apo B levels. Conclusion. Substantial differences in sensitivity and specificity of increased apo B levels were observed in women and men with possible CHD, as well as in various groups of men.https://cardiovascular.elpub.ru/jour/article/view/1478coronary heart diseaseapolipoprotein b concentrationsensitivity and specificity |
| spellingShingle | S. A. Pataraya D. V. Preobrazhensky Clinical role of increased apolipoprotein B levels in coronary heart disease Кардиоваскулярная терапия и профилактика coronary heart disease apolipoprotein b concentration sensitivity and specificity |
| title | Clinical role of increased apolipoprotein B levels in coronary heart disease |
| title_full | Clinical role of increased apolipoprotein B levels in coronary heart disease |
| title_fullStr | Clinical role of increased apolipoprotein B levels in coronary heart disease |
| title_full_unstemmed | Clinical role of increased apolipoprotein B levels in coronary heart disease |
| title_short | Clinical role of increased apolipoprotein B levels in coronary heart disease |
| title_sort | clinical role of increased apolipoprotein b levels in coronary heart disease |
| topic | coronary heart disease apolipoprotein b concentration sensitivity and specificity |
| url | https://cardiovascular.elpub.ru/jour/article/view/1478 |
| work_keys_str_mv | AT sapataraya clinicalroleofincreasedapolipoproteinblevelsincoronaryheartdisease AT dvpreobrazhensky clinicalroleofincreasedapolipoproteinblevelsincoronaryheartdisease |