Endobronchial Mimics of Primary Endobronchial Carcinoma: A Clinical Study of 25 Cases

While endobronchial lesions that present with symptoms of obstruction may be reflective of primary bronchogenic malignancy, there have been a number of reports of bronchial lesions other than primary bronchogenic carcinoma simulating primary endobronchial epithelial malignancy clinically. Twenty-fiv...

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Main Authors: Cynthia M Magro, Patrick Ross
Format: Article
Language:English
Published: Wiley 2005-01-01
Series:Canadian Respiratory Journal
Online Access:http://dx.doi.org/10.1155/2005/563748
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author Cynthia M Magro
Patrick Ross
author_facet Cynthia M Magro
Patrick Ross
author_sort Cynthia M Magro
collection DOAJ
description While endobronchial lesions that present with symptoms of obstruction may be reflective of primary bronchogenic malignancy, there have been a number of reports of bronchial lesions other than primary bronchogenic carcinoma simulating primary endobronchial epithelial malignancy clinically. Twenty-five cases of symptomatic endobronchial disease were encountered with pathological assessment demonstrating an endobronchial process other than carcinoma, representing metastatic disease (breast, colon, renal, head and neck origin), fungal infection, Hodgkin's lymphoma, primary bronchogenic melanoma, lipoma, broncholith and inflammatory pseudopolyp. The present report underscores the potential pathogenetic heterogeneity encountered in lesions presenting with signs and symptoms of endobronchial obstruction, emphasizing the critical role of biopsy for establishing a definitive diagnosis.
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spelling doaj-art-45c059b65ca04802abf2c8e1aa2031642025-08-20T03:36:10ZengWileyCanadian Respiratory Journal1198-22412005-01-0112312312710.1155/2005/563748Endobronchial Mimics of Primary Endobronchial Carcinoma: A Clinical Study of 25 CasesCynthia M Magro0Patrick Ross1Department of Pathology, The Ohio State University, Columbus, Ohio, USADivision of Cardiothoracic Surgery, The Ohio State University, Columbus, Ohio, USAWhile endobronchial lesions that present with symptoms of obstruction may be reflective of primary bronchogenic malignancy, there have been a number of reports of bronchial lesions other than primary bronchogenic carcinoma simulating primary endobronchial epithelial malignancy clinically. Twenty-five cases of symptomatic endobronchial disease were encountered with pathological assessment demonstrating an endobronchial process other than carcinoma, representing metastatic disease (breast, colon, renal, head and neck origin), fungal infection, Hodgkin's lymphoma, primary bronchogenic melanoma, lipoma, broncholith and inflammatory pseudopolyp. The present report underscores the potential pathogenetic heterogeneity encountered in lesions presenting with signs and symptoms of endobronchial obstruction, emphasizing the critical role of biopsy for establishing a definitive diagnosis.http://dx.doi.org/10.1155/2005/563748
spellingShingle Cynthia M Magro
Patrick Ross
Endobronchial Mimics of Primary Endobronchial Carcinoma: A Clinical Study of 25 Cases
Canadian Respiratory Journal
title Endobronchial Mimics of Primary Endobronchial Carcinoma: A Clinical Study of 25 Cases
title_full Endobronchial Mimics of Primary Endobronchial Carcinoma: A Clinical Study of 25 Cases
title_fullStr Endobronchial Mimics of Primary Endobronchial Carcinoma: A Clinical Study of 25 Cases
title_full_unstemmed Endobronchial Mimics of Primary Endobronchial Carcinoma: A Clinical Study of 25 Cases
title_short Endobronchial Mimics of Primary Endobronchial Carcinoma: A Clinical Study of 25 Cases
title_sort endobronchial mimics of primary endobronchial carcinoma a clinical study of 25 cases
url http://dx.doi.org/10.1155/2005/563748
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