Spectrum of Chronic Gastritis Based on Morphological Examination of Gastric Biopsies
Aim: in the retrospective study to assess the frequency of various gastritis variants based on the results of morphological examination of gastric biopsies over a 5-year observation period.Methods. The study included 3162 individuals who underwent esophagogastroduodenoscopy with biopsy collection be...
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| Format: | Article |
| Language: | Russian |
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Gastro LLC
2024-05-01
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| Series: | Российский журнал гастроэнтерологии, гепатологии, колопроктологии |
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| Online Access: | https://www.gastro-j.ru/jour/article/view/975 |
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| author | А. S. Tertychnyy Т. L. Lapina D. Р. Nagornaya N. V. Pachuashvili А. Р. Kiryukhin А. А. Fedorenko Р. V. Pavlov D. D. Protsenko V. Т. Ivashkin |
| author_facet | А. S. Tertychnyy Т. L. Lapina D. Р. Nagornaya N. V. Pachuashvili А. Р. Kiryukhin А. А. Fedorenko Р. V. Pavlov D. D. Protsenko V. Т. Ivashkin |
| author_sort | А. S. Tertychnyy |
| collection | DOAJ |
| description | Aim: in the retrospective study to assess the frequency of various gastritis variants based on the results of morphological examination of gastric biopsies over a 5-year observation period.Methods. The study included 3162 individuals who underwent esophagogastroduodenoscopy with biopsy collection between 2017 and 2022. Pathological examination of biopsies was conducted using the updated Sydney system, determining the histological variant and, when possible, the etiology of gastritis. In some cases, chronic gastritis was assessed using the OLGA/OLGIM system.Results. The most frequently diagnosed type was active H. pylori-associated gastritis (36.7 %), followed by chronic atrophic gastritis with intestinal metaplasia in cases where H. pylori infection was not detected (28.4 %), including immunohistochemical examination, classified as gastritis after successful H. pylori eradication. Atrophic forms of chronic gastritis constituted 34.8 %. Minimal or mild changes close to normal histological characteristics were оbserved in 19.2 % of patients. Reactive gastropathy was present in 7.6 % of cases. Autoimmune gastritis ranked fourth in frequency, with a relatively high percentage of observations (8.6 %).Conclusion. According to the analysis of gastric biopsies in the Russian population, a high frequency of H. pylori-associated gastritis was observed, and autoimmune gastritis is not uncommon. The high prevalence of atrophic gastritis emphasizes the importance of dynamic patient monitoring within cancer prevention programs. |
| format | Article |
| id | doaj-art-45a5b11f5640414db235af5ab10138f3 |
| institution | Kabale University |
| issn | 1382-4376 2658-6673 |
| language | Russian |
| publishDate | 2024-05-01 |
| publisher | Gastro LLC |
| record_format | Article |
| series | Российский журнал гастроэнтерологии, гепатологии, колопроктологии |
| spelling | doaj-art-45a5b11f5640414db235af5ab10138f32025-02-10T16:14:38ZrusGastro LLCРоссийский журнал гастроэнтерологии, гепатологии, колопроктологии1382-43762658-66732024-05-01342455610.22416/1382-4376-2024-34-2-45-56682Spectrum of Chronic Gastritis Based on Morphological Examination of Gastric BiopsiesА. S. Tertychnyy0Т. L. Lapina1D. Р. Nagornaya2N. V. Pachuashvili3А. Р. Kiryukhin4А. А. Fedorenko5Р. V. Pavlov6D. D. Protsenko7V. Т. Ivashkin8I.M. Sechenov First Moscow State Medical University (Sechenov University)I.M. Sechenov First Moscow State Medical University (Sechenov University)I.M. Sechenov First Moscow State Medical University (Sechenov University)I.M. Sechenov First Moscow State Medical University (Sechenov University)I.M. Sechenov First Moscow State Medical University (Sechenov University)I.M. Sechenov First Moscow State Medical University (Sechenov University)I.M. Sechenov First Moscow State Medical University (Sechenov University)I.M. Sechenov First Moscow State Medical University (Sechenov University)I.M. Sechenov First Moscow State Medical University (Sechenov University)Aim: in the retrospective study to assess the frequency of various gastritis variants based on the results of morphological examination of gastric biopsies over a 5-year observation period.Methods. The study included 3162 individuals who underwent esophagogastroduodenoscopy with biopsy collection between 2017 and 2022. Pathological examination of biopsies was conducted using the updated Sydney system, determining the histological variant and, when possible, the etiology of gastritis. In some cases, chronic gastritis was assessed using the OLGA/OLGIM system.Results. The most frequently diagnosed type was active H. pylori-associated gastritis (36.7 %), followed by chronic atrophic gastritis with intestinal metaplasia in cases where H. pylori infection was not detected (28.4 %), including immunohistochemical examination, classified as gastritis after successful H. pylori eradication. Atrophic forms of chronic gastritis constituted 34.8 %. Minimal or mild changes close to normal histological characteristics were оbserved in 19.2 % of patients. Reactive gastropathy was present in 7.6 % of cases. Autoimmune gastritis ranked fourth in frequency, with a relatively high percentage of observations (8.6 %).Conclusion. According to the analysis of gastric biopsies in the Russian population, a high frequency of H. pylori-associated gastritis was observed, and autoimmune gastritis is not uncommon. The high prevalence of atrophic gastritis emphasizes the importance of dynamic patient monitoring within cancer prevention programs.https://www.gastro-j.ru/jour/article/view/975gastritish. pylorireactive gastropathyatrophic gastritis, autoimmune gastritis |
| spellingShingle | А. S. Tertychnyy Т. L. Lapina D. Р. Nagornaya N. V. Pachuashvili А. Р. Kiryukhin А. А. Fedorenko Р. V. Pavlov D. D. Protsenko V. Т. Ivashkin Spectrum of Chronic Gastritis Based on Morphological Examination of Gastric Biopsies Российский журнал гастроэнтерологии, гепатологии, колопроктологии gastritis h. pylori reactive gastropathy atrophic gastritis, autoimmune gastritis |
| title | Spectrum of Chronic Gastritis Based on Morphological Examination of Gastric Biopsies |
| title_full | Spectrum of Chronic Gastritis Based on Morphological Examination of Gastric Biopsies |
| title_fullStr | Spectrum of Chronic Gastritis Based on Morphological Examination of Gastric Biopsies |
| title_full_unstemmed | Spectrum of Chronic Gastritis Based on Morphological Examination of Gastric Biopsies |
| title_short | Spectrum of Chronic Gastritis Based on Morphological Examination of Gastric Biopsies |
| title_sort | spectrum of chronic gastritis based on morphological examination of gastric biopsies |
| topic | gastritis h. pylori reactive gastropathy atrophic gastritis, autoimmune gastritis |
| url | https://www.gastro-j.ru/jour/article/view/975 |
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