Differential effects of inulin and fructooligosaccharides on gut microbiota composition and glycemic metabolism in overweight/obese and healthy individuals: a randomized, double-blind clinical trial

Differential effects of inulin and fructooligosaccharides on gut microbiota composition and glycemic metabolism in overweight/obese and healthy individuals: a randomized, double-blind clinical trial

Abstract Background Modulating the gut microbiota with prebiotics is a promising strategy for managing metabolic diseases. However, the clinical effects on glycemic metabolism across different populations remain uncertain. In this study, we conducted a randomized, double-blind investigation to exami...

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Bibliographic Details
Main Authors: Jie Li, Feitong Liu, Yuemei Luo, Anisha Wijeyesekera, Shan Wang, Xiaojiao Chen, Yamei Lv, Jing Jin, Huafang Sheng, Guopan Wang, Yuanan Wei, Zhuang Li, Muxuan Chen, Hongwei Zhou
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Medicine
Subjects:
Prebiotics
Inulin (INU)
Fructo-oligosaccharides (FOS)
Glycemic metabolism
Overweight/obese
Gut microbiota
Online Access:https://doi.org/10.1186/s12916-025-04189-6
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