A comprehensive evaluation of potential lung function associated genes in the SpiroMeta general population sample.

A comprehensive evaluation of potential lung function associated genes in the SpiroMeta general population sample.

<h4>Rationale</h4>Lung function measures are heritable traits that predict population morbidity and mortality and are essential for the diagnosis of chronic obstructive pulmonary disease (COPD). Variations in many genes have been reported to affect these traits, but attempts at replicati...

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Main Authors: Ma'en Obeidat, Louise V Wain, Nick Shrine, Noor Kalsheker, Maria Soler Artigas, Emmanouela Repapi, Paul R Burton, Toby Johnson, Adaikalavan Ramasamy, Jing Hua Zhao, Guangju Zhai, Jennifer E Huffman, Veronique Vitart, Eva Albrecht, Wilmar Igl, Anna-Liisa Hartikainen, Anneli Pouta, Gemma Cadby, Jennie Hui, Lyle J Palmer, David Hadley, Wendy L McArdle, Alicja R Rudnicka, Inês Barroso, Ruth J F Loos, Nicholas J Wareham, Massimo Mangino, Nicole Soranzo, Tim D Spector, Sven Gläser, Georg Homuth, Henry Völzke, Panos Deloukas, Raquel Granell, John Henderson, Ivica Grkovic, Stipan Jankovic, Lina Zgaga, Ozren Polašek, Igor Rudan, Alan F Wright, Harry Campbell, Sarah H Wild, James F Wilson, Joachim Heinrich, Medea Imboden, Nicole M Probst-Hensch, Ulf Gyllensten, Åsa Johansson, Ghazal Zaboli, Linda Mustelin, Taina Rantanen, Ida Surakka, Jaakko Kaprio, Marjo-Riitta Jarvelin, Caroline Hayward, David M Evans, Beate Koch, Arthur William Musk, Paul Elliott, David P Strachan, Martin D Tobin, Ian Sayers, Ian P Hall, SpiroMeta Consortium
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0019382
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