Postoperative Pain and Blood Loss of Non-use Compared to Partial-use of a Tourniquet in Bilateral Total Knee Replacement: A Randomized Control Trial

Objective: This study aimed to compare the effects of non-tourniquet usage (NTU) and partial-tourniquet usage (before osteotomy in operation; BOO) of a tourniquet in bilateral total knee arthroplasty (TKA) on postoperative pain and complications. Materials and Methods: A prospective randomized co...

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Main Authors: Thada Wipatasinlapin, Surapol Atiprayoon, Peerawin Atiprayoon
Format: Article
Language:English
Published: Faculty of Medicine Siriraj Hospital 2025-06-01
Series:Siriraj Medical Journal
Subjects:
Online Access:https://he02.tci-thaijo.org/index.php/sirirajmedj/article/view/271055
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author Thada Wipatasinlapin
Surapol Atiprayoon
Peerawin Atiprayoon
author_facet Thada Wipatasinlapin
Surapol Atiprayoon
Peerawin Atiprayoon
author_sort Thada Wipatasinlapin
collection DOAJ
description Objective: This study aimed to compare the effects of non-tourniquet usage (NTU) and partial-tourniquet usage (before osteotomy in operation; BOO) of a tourniquet in bilateral total knee arthroplasty (TKA) on postoperative pain and complications. Materials and Methods: A prospective randomized control trial with cross-over design was designed to compare the effect of NTU vs BOO in the patients underwent bilateral TKA. The opioid consumption and pain score were primary outcomes. Blood loss, the number of wound complications, the postoperative complications and time to ambulation were secondary outcomes. Results: NTU group showed a significantly reduction in opioid consumption (14.8 ± 8.3 mg) as compared to that of BOO group (24.6 ± 10.8 mg) in the postoperative 24 hours. The postoperative pain score was significantly lower by the first, second, third and fourth day postoperative in NTU group (3.2, 3.9, 3.5, 2.3) compared to BOO group (4.3, 5.6, 4.8, and 4.1). There was no significant difference in blood loss between the groups. Early postoperative wound ecchymosis was found in BOO group (5 knees), more than in the NTU group (1 knee) with statistical significance. Conclusion: Performing total knee arthroplasty (TKA) without using a tourniquet, can reduce particularly the magnitude difference in pain and opioid consumption better than using the tourniquet as well as lack of significant difference in blood loss. This will allow for future clinical implications to determine that NTU may be preferable due to reduced postoperative pain and fewer postoperative wound complications.
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spelling doaj-art-4588b59fbed34f209c047aad712f07712025-08-20T02:39:01ZengFaculty of Medicine Siriraj HospitalSiriraj Medical Journal2228-80822025-06-0177610.33192/smj.v77i6.271055Postoperative Pain and Blood Loss of Non-use Compared to Partial-use of a Tourniquet in Bilateral Total Knee Replacement: A Randomized Control TrialThada Wipatasinlapin0Surapol Atiprayoon1Peerawin Atiprayoon2Queen Savang Vadhana Memorial Hospital, Bangkok, ThailandQueen Savang Vadhana Memorial Hospital, Bangkok, ThailandTriam Udom Suksa School, Bangkok, Thailand Objective: This study aimed to compare the effects of non-tourniquet usage (NTU) and partial-tourniquet usage (before osteotomy in operation; BOO) of a tourniquet in bilateral total knee arthroplasty (TKA) on postoperative pain and complications. Materials and Methods: A prospective randomized control trial with cross-over design was designed to compare the effect of NTU vs BOO in the patients underwent bilateral TKA. The opioid consumption and pain score were primary outcomes. Blood loss, the number of wound complications, the postoperative complications and time to ambulation were secondary outcomes. Results: NTU group showed a significantly reduction in opioid consumption (14.8 ± 8.3 mg) as compared to that of BOO group (24.6 ± 10.8 mg) in the postoperative 24 hours. The postoperative pain score was significantly lower by the first, second, third and fourth day postoperative in NTU group (3.2, 3.9, 3.5, 2.3) compared to BOO group (4.3, 5.6, 4.8, and 4.1). There was no significant difference in blood loss between the groups. Early postoperative wound ecchymosis was found in BOO group (5 knees), more than in the NTU group (1 knee) with statistical significance. Conclusion: Performing total knee arthroplasty (TKA) without using a tourniquet, can reduce particularly the magnitude difference in pain and opioid consumption better than using the tourniquet as well as lack of significant difference in blood loss. This will allow for future clinical implications to determine that NTU may be preferable due to reduced postoperative pain and fewer postoperative wound complications. https://he02.tci-thaijo.org/index.php/sirirajmedj/article/view/271055Total knee arthroplastyBilateralPainTourniquet
spellingShingle Thada Wipatasinlapin
Surapol Atiprayoon
Peerawin Atiprayoon
Postoperative Pain and Blood Loss of Non-use Compared to Partial-use of a Tourniquet in Bilateral Total Knee Replacement: A Randomized Control Trial
Siriraj Medical Journal
Total knee arthroplasty
Bilateral
Pain
Tourniquet
title Postoperative Pain and Blood Loss of Non-use Compared to Partial-use of a Tourniquet in Bilateral Total Knee Replacement: A Randomized Control Trial
title_full Postoperative Pain and Blood Loss of Non-use Compared to Partial-use of a Tourniquet in Bilateral Total Knee Replacement: A Randomized Control Trial
title_fullStr Postoperative Pain and Blood Loss of Non-use Compared to Partial-use of a Tourniquet in Bilateral Total Knee Replacement: A Randomized Control Trial
title_full_unstemmed Postoperative Pain and Blood Loss of Non-use Compared to Partial-use of a Tourniquet in Bilateral Total Knee Replacement: A Randomized Control Trial
title_short Postoperative Pain and Blood Loss of Non-use Compared to Partial-use of a Tourniquet in Bilateral Total Knee Replacement: A Randomized Control Trial
title_sort postoperative pain and blood loss of non use compared to partial use of a tourniquet in bilateral total knee replacement a randomized control trial
topic Total knee arthroplasty
Bilateral
Pain
Tourniquet
url https://he02.tci-thaijo.org/index.php/sirirajmedj/article/view/271055
work_keys_str_mv AT thadawipatasinlapin postoperativepainandbloodlossofnonusecomparedtopartialuseofatourniquetinbilateraltotalkneereplacementarandomizedcontroltrial
AT surapolatiprayoon postoperativepainandbloodlossofnonusecomparedtopartialuseofatourniquetinbilateraltotalkneereplacementarandomizedcontroltrial
AT peerawinatiprayoon postoperativepainandbloodlossofnonusecomparedtopartialuseofatourniquetinbilateraltotalkneereplacementarandomizedcontroltrial