Tumor-associated macrophage-derived exosome miR-194 confers cisplatin resistance in GC cells
Abstract Objective At all stages of gastric cancer (GC), cisplatin is the first-line chemotherapeutic agent, but its efficacy remains limited, with a response rate of less than 20%, largely because of resistance to the drug. It aims to determine whether macrophage-derived exosomes are involved in th...
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Main Authors: | Yi Zhou, Yang-cheng Sun, Qiong-yan Zhang, Jing Wang, Xian-ya Zhu, Xiang-yu Su |
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Format: | Article |
Language: | English |
Published: |
BMC
2025-02-01
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Series: | European Journal of Medical Research |
Subjects: | |
Online Access: | https://doi.org/10.1186/s40001-025-02329-5 |
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