Synthesis, Cytotoxic and Genotoxic Evaluation of Drug-Loaded Silver Nanoparticles with Mebeverine and Its Analog

Synthesis, Cytotoxic and Genotoxic Evaluation of Drug-Loaded Silver Nanoparticles with Mebeverine and Its Analog

<b>Background:</b> Irritable bowel syndrome (IBS) is a prevalent gastrointestinal disorder with a complex pathogenesis that necessitates innovative therapeutic approaches for effective management. Among the commonly used treatments, mebeverine (MBH), an antispasmodic, is widely prescribe...

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Main Authors: Mihaela Stoyanova, Miglena Milusheva, Milena Georgieva, Penyo Ivanov, George Miloshev, Natalia Krasteva, Kamelia Hristova-Panusheva, Mehran Feizi-Dehnayebi, Ghodsi Mohammadi Ziarani, Kirila Stojnova, Slava Tsoneva, Mina Todorova, Stoyanka Nikolova
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Pharmaceuticals
Subjects:
silver nanoparticles
cytotoxicity
genotoxicity
in vitro
in silico
molecular docking
Online Access:https://www.mdpi.com/1424-8247/18/3/397
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