Buruli ulcer in Australia: Evidence for a new endemic focus at Batemans Bay, New South Wales.

We describe two locally acquired cases of Mycobacterium ulcerans infection (Buruli ulcer) in the town of Batemans Bay on the east coast of New South Wales (NSW), Australia, 150 km north of Eden, the only other place in NSW where Buruli ulcer has likely been locally acquired. Genomic analysis showed...

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Main Authors: Mehrab E Hossain, Caitlin Keighley, Andrew H Buultjens, Jessica L Porter, Paul D R Johnson, Timothy P Stinear, Maria Globan, Caroline J Lavender, Jake A Lacey, Norelle L Sherry, Anton Forsyth, Mark Formby, Ian Marr
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-12-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0012702
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author Mehrab E Hossain
Caitlin Keighley
Andrew H Buultjens
Jessica L Porter
Paul D R Johnson
Timothy P Stinear
Maria Globan
Caroline J Lavender
Jake A Lacey
Norelle L Sherry
Anton Forsyth
Mark Formby
Ian Marr
author_facet Mehrab E Hossain
Caitlin Keighley
Andrew H Buultjens
Jessica L Porter
Paul D R Johnson
Timothy P Stinear
Maria Globan
Caroline J Lavender
Jake A Lacey
Norelle L Sherry
Anton Forsyth
Mark Formby
Ian Marr
author_sort Mehrab E Hossain
collection DOAJ
description We describe two locally acquired cases of Mycobacterium ulcerans infection (Buruli ulcer) in the town of Batemans Bay on the east coast of New South Wales (NSW), Australia, 150 km north of Eden, the only other place in NSW where Buruli ulcer has likely been locally acquired. Genomic analysis showed that the bacterial isolates from the cases were identical but belonged to a phylogenetically distinct M. ulcerans clade that was most closely related to the isolate from the earlier case in Eden to the south. It is proposed that Batemans Bay is a new endemic focus of human Buruli ulcer transmission.
format Article
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institution DOAJ
issn 1935-2727
1935-2735
language English
publishDate 2024-12-01
publisher Public Library of Science (PLoS)
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series PLoS Neglected Tropical Diseases
spelling doaj-art-456b10e866b34fbebca1ea704329bceb2025-08-20T02:59:18ZengPublic Library of Science (PLoS)PLoS Neglected Tropical Diseases1935-27271935-27352024-12-011812e001270210.1371/journal.pntd.0012702Buruli ulcer in Australia: Evidence for a new endemic focus at Batemans Bay, New South Wales.Mehrab E HossainCaitlin KeighleyAndrew H BuultjensJessica L PorterPaul D R JohnsonTimothy P StinearMaria GlobanCaroline J LavenderJake A LaceyNorelle L SherryAnton ForsythMark FormbyIan MarrWe describe two locally acquired cases of Mycobacterium ulcerans infection (Buruli ulcer) in the town of Batemans Bay on the east coast of New South Wales (NSW), Australia, 150 km north of Eden, the only other place in NSW where Buruli ulcer has likely been locally acquired. Genomic analysis showed that the bacterial isolates from the cases were identical but belonged to a phylogenetically distinct M. ulcerans clade that was most closely related to the isolate from the earlier case in Eden to the south. It is proposed that Batemans Bay is a new endemic focus of human Buruli ulcer transmission.https://doi.org/10.1371/journal.pntd.0012702
spellingShingle Mehrab E Hossain
Caitlin Keighley
Andrew H Buultjens
Jessica L Porter
Paul D R Johnson
Timothy P Stinear
Maria Globan
Caroline J Lavender
Jake A Lacey
Norelle L Sherry
Anton Forsyth
Mark Formby
Ian Marr
Buruli ulcer in Australia: Evidence for a new endemic focus at Batemans Bay, New South Wales.
PLoS Neglected Tropical Diseases
title Buruli ulcer in Australia: Evidence for a new endemic focus at Batemans Bay, New South Wales.
title_full Buruli ulcer in Australia: Evidence for a new endemic focus at Batemans Bay, New South Wales.
title_fullStr Buruli ulcer in Australia: Evidence for a new endemic focus at Batemans Bay, New South Wales.
title_full_unstemmed Buruli ulcer in Australia: Evidence for a new endemic focus at Batemans Bay, New South Wales.
title_short Buruli ulcer in Australia: Evidence for a new endemic focus at Batemans Bay, New South Wales.
title_sort buruli ulcer in australia evidence for a new endemic focus at batemans bay new south wales
url https://doi.org/10.1371/journal.pntd.0012702
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