Modulation of cerebrospinal fluid secretion facilitated by serotonergic and noradrenergic receptors in the rat choroid plexus

Modulation of cerebrospinal fluid secretion facilitated by serotonergic and noradrenergic receptors in the rat choroid plexus

Abstract Background The intracranial pressure (ICP) increases at night, partly due to an elevated rate of cerebrospinal fluid (CSF) secretion, which may have therapeutic implications for pressure-related disorders. With similar diurnal regulation in nocturnal rodents and diurnal humans, the diurnall...

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Bibliographic Details
Main Authors: Beatriche L. Edelbo, Annette B. Steffensen, Eszter O. Revesz, Søren N. Andreassen, Nanna MacAulay
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Fluids and Barriers of the CNS
Subjects:
CSF
Diurnal
ICP
Choroid plexus
Noradrenaline
Online Access:https://doi.org/10.1186/s12987-025-00666-5
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