DEB-TACE combined with ici for advanced squamous cell carcinoma of the skin: a case report
We report the case of an older female patient with squamous cell carcinoma of the skin, cTXN1M0, who initially presented with a mass of approximately 4.5 cm in diameter in the left temporal region, which had a tendency to break and bleed. Given the patient’s poor general status and ECOG score of gra...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2025-04-01
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| Series: | Frontiers in Oncology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fonc.2025.1529976/full |
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| author | Zhuo Wu Xuezhe Piao Dongxu Kang Lan Jin Qiang Xu Dehao Jin Longzhen Piao |
| author_facet | Zhuo Wu Xuezhe Piao Dongxu Kang Lan Jin Qiang Xu Dehao Jin Longzhen Piao |
| author_sort | Zhuo Wu |
| collection | DOAJ |
| description | We report the case of an older female patient with squamous cell carcinoma of the skin, cTXN1M0, who initially presented with a mass of approximately 4.5 cm in diameter in the left temporal region, which had a tendency to break and bleed. Given the patient’s poor general status and ECOG score of grade 2, it was considered that she could not tolerate systemic chemotherapy. Therefore, we applied drug-eluting beads transarterial chemoembolization combined with immune checkpoint inhibitors to treat this patient and unexpectedly found that this regimen resulted in complete classified remission and in partial pathological response without significant adverse events. |
| format | Article |
| id | doaj-art-4545c76bb272489ba6b1f2d6e42cde57 |
| institution | OA Journals |
| issn | 2234-943X |
| language | English |
| publishDate | 2025-04-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Oncology |
| spelling | doaj-art-4545c76bb272489ba6b1f2d6e42cde572025-08-20T02:18:43ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2025-04-011510.3389/fonc.2025.15299761529976DEB-TACE combined with ici for advanced squamous cell carcinoma of the skin: a case reportZhuo Wu0Xuezhe Piao1Dongxu Kang2Lan Jin3Qiang Xu4Dehao Jin5Longzhen Piao6Department of Oncology, Yanbian University Hospital, Yanji, Jilin, ChinaDepartment of Oncology, Yanbian University Hospital, Yanji, Jilin, ChinaDepartment of Oncology, Yanbian University Hospital, Yanji, Jilin, ChinaDepartment of Oncology, Yanbian University Hospital, Yanji, Jilin, ChinaDepartment of Oncology, Yanbian University Hospital, Yanji, Jilin, ChinaDepartment of Intervention, Yanbian University Hospital, Yanji, Jilin, ChinaDepartment of Oncology, Yanbian University Hospital, Yanji, Jilin, ChinaWe report the case of an older female patient with squamous cell carcinoma of the skin, cTXN1M0, who initially presented with a mass of approximately 4.5 cm in diameter in the left temporal region, which had a tendency to break and bleed. Given the patient’s poor general status and ECOG score of grade 2, it was considered that she could not tolerate systemic chemotherapy. Therefore, we applied drug-eluting beads transarterial chemoembolization combined with immune checkpoint inhibitors to treat this patient and unexpectedly found that this regimen resulted in complete classified remission and in partial pathological response without significant adverse events.https://www.frontiersin.org/articles/10.3389/fonc.2025.1529976/fullDEB-TACEICICSCCcomplete remissioncase report |
| spellingShingle | Zhuo Wu Xuezhe Piao Dongxu Kang Lan Jin Qiang Xu Dehao Jin Longzhen Piao DEB-TACE combined with ici for advanced squamous cell carcinoma of the skin: a case report Frontiers in Oncology DEB-TACE ICI CSCC complete remission case report |
| title | DEB-TACE combined with ici for advanced squamous cell carcinoma of the skin: a case report |
| title_full | DEB-TACE combined with ici for advanced squamous cell carcinoma of the skin: a case report |
| title_fullStr | DEB-TACE combined with ici for advanced squamous cell carcinoma of the skin: a case report |
| title_full_unstemmed | DEB-TACE combined with ici for advanced squamous cell carcinoma of the skin: a case report |
| title_short | DEB-TACE combined with ici for advanced squamous cell carcinoma of the skin: a case report |
| title_sort | deb tace combined with ici for advanced squamous cell carcinoma of the skin a case report |
| topic | DEB-TACE ICI CSCC complete remission case report |
| url | https://www.frontiersin.org/articles/10.3389/fonc.2025.1529976/full |
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