Effects of different exercise modalities on oxygenation stress, inflammatory factors, and drug craving in drug users during the audit period
Objective: To explore the effects of different exercise modalities on drug craving and the oxidative stress-inflammatory mechanisms in female addicts during rehabilitation. Methods: Forty female drug users were randomly assigned to yoga, meditation, physical fitness, or control groups (n=10 eac...
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Nicolaus Copernicus University in Toruń
2025-05-01
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| Series: | Quality in Sport |
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| Online Access: | https://apcz.umk.pl/QS/article/view/60144 |
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| author | Yanmei Chen 舜杰shunjie 武 |
| author_facet | Yanmei Chen 舜杰shunjie 武 |
| author_sort | Yanmei Chen |
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Objective:
To explore the effects of different exercise modalities on drug craving and the oxidative stress-inflammatory mechanisms in female addicts during rehabilitation. Methods: Forty female drug users were randomly assigned to yoga, meditation, physical fitness, or control groups (n=10 each). A 12-week intervention (3 sessions/week, 1 h/session) was conducted. Serum levels of malondialdehyde (MDA), homocysteine (HCY), tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6), IL-1, and intercellular adhesion molecule-1 (ICAM-1) were measured pre- and post-intervention. Drug craving was assessed via a visual analog scale (VAS). Results: (1) Female addicts exhibited elevated oxidative stress (MDA, HCY) and inflammatory markers (TNF-α, IL-6, IL-1, ICAM-1) compared to healthy individuals; (2) Post-intervention, these biomarkers significantly decreased in the yoga, meditation, and physical fitness groups (p<0.05); (3) VAS scores in all exercise groups showed marked reduction (p<0.01). Conclusion: Oxidative stress and inflammatory responses are present in female addicts during rehabilitation. Twelve weeks of exercise (yoga, meditation, or fitness training) effectively reduces these biomarkers, promotes inflammatory homeostasis, and alleviates drug craving, with comparable efficacy across modalities.
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| format | Article |
| id | doaj-art-4533c385d279486e9fe7c9b97f86ff6f |
| institution | OA Journals |
| issn | 2450-3118 |
| language | English |
| publishDate | 2025-05-01 |
| publisher | Nicolaus Copernicus University in Toruń |
| record_format | Article |
| series | Quality in Sport |
| spelling | doaj-art-4533c385d279486e9fe7c9b97f86ff6f2025-08-20T02:15:32ZengNicolaus Copernicus University in ToruńQuality in Sport2450-31182025-05-014110.12775/QS.2025.41.60144Effects of different exercise modalities on oxygenation stress, inflammatory factors, and drug craving in drug users during the audit periodYanmei Chen0https://orcid.org/0009-0001-1566-3822舜杰shunjie 武1https://orcid.org/0009-0005-4110-2059School of Physical Education, Southwest University, Research Interests: Exercise Monitoring, Exercise and Drug RehabilitationCollege of Physical Education, Southwest University, Chongqing, China Objective: To explore the effects of different exercise modalities on drug craving and the oxidative stress-inflammatory mechanisms in female addicts during rehabilitation. Methods: Forty female drug users were randomly assigned to yoga, meditation, physical fitness, or control groups (n=10 each). A 12-week intervention (3 sessions/week, 1 h/session) was conducted. Serum levels of malondialdehyde (MDA), homocysteine (HCY), tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6), IL-1, and intercellular adhesion molecule-1 (ICAM-1) were measured pre- and post-intervention. Drug craving was assessed via a visual analog scale (VAS). Results: (1) Female addicts exhibited elevated oxidative stress (MDA, HCY) and inflammatory markers (TNF-α, IL-6, IL-1, ICAM-1) compared to healthy individuals; (2) Post-intervention, these biomarkers significantly decreased in the yoga, meditation, and physical fitness groups (p<0.05); (3) VAS scores in all exercise groups showed marked reduction (p<0.01). Conclusion: Oxidative stress and inflammatory responses are present in female addicts during rehabilitation. Twelve weeks of exercise (yoga, meditation, or fitness training) effectively reduces these biomarkers, promotes inflammatory homeostasis, and alleviates drug craving, with comparable efficacy across modalities. https://apcz.umk.pl/QS/article/view/60144exercisedrug usersinflammatory factorsdrug craving |
| spellingShingle | Yanmei Chen 舜杰shunjie 武 Effects of different exercise modalities on oxygenation stress, inflammatory factors, and drug craving in drug users during the audit period Quality in Sport exercise drug users inflammatory factors drug craving |
| title | Effects of different exercise modalities on oxygenation stress, inflammatory factors, and drug craving in drug users during the audit period |
| title_full | Effects of different exercise modalities on oxygenation stress, inflammatory factors, and drug craving in drug users during the audit period |
| title_fullStr | Effects of different exercise modalities on oxygenation stress, inflammatory factors, and drug craving in drug users during the audit period |
| title_full_unstemmed | Effects of different exercise modalities on oxygenation stress, inflammatory factors, and drug craving in drug users during the audit period |
| title_short | Effects of different exercise modalities on oxygenation stress, inflammatory factors, and drug craving in drug users during the audit period |
| title_sort | effects of different exercise modalities on oxygenation stress inflammatory factors and drug craving in drug users during the audit period |
| topic | exercise drug users inflammatory factors drug craving |
| url | https://apcz.umk.pl/QS/article/view/60144 |
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