Liberation from Dialysis Dependence in a Patient with HIV-Associated Nephropathy (HIVAN) after Combined Antiretroviral Therapy (cART)
Prior to the advent of combined antiretroviral therapy (cART), human immunodeficiency virus-associated nephropathy (HIVAN) was inevitably associated with rapidly progressive renal failure and dialysis dependence. HIV-1 seropositive patients often met with untimely deaths due to complications of end-...
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| Format: | Article |
| Language: | English |
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Wiley
2020-01-01
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| Series: | Case Reports in Nephrology |
| Online Access: | http://dx.doi.org/10.1155/2020/7294765 |
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| author | Virin Ramoutar Raafat Makary Malleswari Ravi Leighton James Charles Heilig |
| author_facet | Virin Ramoutar Raafat Makary Malleswari Ravi Leighton James Charles Heilig |
| author_sort | Virin Ramoutar |
| collection | DOAJ |
| description | Prior to the advent of combined antiretroviral therapy (cART), human immunodeficiency virus-associated nephropathy (HIVAN) was inevitably associated with rapidly progressive renal failure and dialysis dependence. HIV-1 seropositive patients often met with untimely deaths due to complications of end-stage renal disease (ESRD), opportunistic infections, or other HIV-related end-organ failure. Although the association between cART and improved outcomes in HIVAN has been recognized for over 20 years, no randomized trials have specifically examined this effect to date. In terms of reversal of dialysis-dependent renal failure after cART initiation, only a handful of case reports exist. The authors report a case of a 44-year-old Latino male requiring thrice-weekly haemodialysis in the setting of biopsy-proven HIVAN who was able to stop dialysis in 7 months after being initiated on cART. |
| format | Article |
| id | doaj-art-45194de10fcb405fa060fa7b361a7c7b |
| institution | Kabale University |
| issn | 2090-6641 2090-665X |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Nephrology |
| spelling | doaj-art-45194de10fcb405fa060fa7b361a7c7b2025-08-20T03:36:44ZengWileyCase Reports in Nephrology2090-66412090-665X2020-01-01202010.1155/2020/72947657294765Liberation from Dialysis Dependence in a Patient with HIV-Associated Nephropathy (HIVAN) after Combined Antiretroviral Therapy (cART)Virin Ramoutar0Raafat Makary1Malleswari Ravi2Leighton James3Charles Heilig4Nephrologist & Infectious Disease Specialist, Cumberland Kidney Specialists, Cookeville, TN, USAPathology Department, University of Florida, Jacksonville, FL, USADivision of Infectious Disease, University of Florida, Jacksonville, FL, USADivision of Nephrology, Medical College of Georgia, Augusta University, Augusta, GA, USADivision of Nephrology, University of Florida, Jacksonville, FL, USAPrior to the advent of combined antiretroviral therapy (cART), human immunodeficiency virus-associated nephropathy (HIVAN) was inevitably associated with rapidly progressive renal failure and dialysis dependence. HIV-1 seropositive patients often met with untimely deaths due to complications of end-stage renal disease (ESRD), opportunistic infections, or other HIV-related end-organ failure. Although the association between cART and improved outcomes in HIVAN has been recognized for over 20 years, no randomized trials have specifically examined this effect to date. In terms of reversal of dialysis-dependent renal failure after cART initiation, only a handful of case reports exist. The authors report a case of a 44-year-old Latino male requiring thrice-weekly haemodialysis in the setting of biopsy-proven HIVAN who was able to stop dialysis in 7 months after being initiated on cART.http://dx.doi.org/10.1155/2020/7294765 |
| spellingShingle | Virin Ramoutar Raafat Makary Malleswari Ravi Leighton James Charles Heilig Liberation from Dialysis Dependence in a Patient with HIV-Associated Nephropathy (HIVAN) after Combined Antiretroviral Therapy (cART) Case Reports in Nephrology |
| title | Liberation from Dialysis Dependence in a Patient with HIV-Associated Nephropathy (HIVAN) after Combined Antiretroviral Therapy (cART) |
| title_full | Liberation from Dialysis Dependence in a Patient with HIV-Associated Nephropathy (HIVAN) after Combined Antiretroviral Therapy (cART) |
| title_fullStr | Liberation from Dialysis Dependence in a Patient with HIV-Associated Nephropathy (HIVAN) after Combined Antiretroviral Therapy (cART) |
| title_full_unstemmed | Liberation from Dialysis Dependence in a Patient with HIV-Associated Nephropathy (HIVAN) after Combined Antiretroviral Therapy (cART) |
| title_short | Liberation from Dialysis Dependence in a Patient with HIV-Associated Nephropathy (HIVAN) after Combined Antiretroviral Therapy (cART) |
| title_sort | liberation from dialysis dependence in a patient with hiv associated nephropathy hivan after combined antiretroviral therapy cart |
| url | http://dx.doi.org/10.1155/2020/7294765 |
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