Tanshinlactone triggers methuosis in breast cancer cells via NRF2 activation

Tanshinlactone triggers methuosis in breast cancer cells via NRF2 activation

BackgroundTanshinlactone is a compound derived from the herb Salvia miltiorrhiza. Breast cancer is the most prevalent malignancy among women globally. While significant strides have been made in breast cancer management, these interventions are often impeded by substantial adverse effects that under...

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Bibliographic Details
Main Authors: Wanjun Lin, Zifeng Huang, Xuening Zhang, Dayuan Zheng, Yanchao Yang, Meina Shi, Dongfang Yang, Tong Chu, Wenzhe Ma
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Pharmacology
Subjects:
tanshinlactone
breast cancer
catastrophic macropinocytosis
methuosis
NRF2 activation
drug resistance
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2024.1534217/full
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