Rosiglitazone Attenuated Endothelin-1-Induced Vasoconstriction of Pulmonary Arteries in the Rat Model of Pulmonary Arterial Hypertension via Differential Regulation of ET-1 Receptors
Pulmonary arterial hypertension (PAH) is a fatal disease characterized by a progressive increase in pulmonary arterial pressure leading to right ventricular failure and death. Activation of the endothelin (ET)-1 system has been demonstrated in plasma and lung tissue of PAH patients as well as in ani...
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Main Authors: | Yahan Liu, Xiao Yu Tian, Yu Huang, Nanping Wang |
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Format: | Article |
Language: | English |
Published: |
Wiley
2014-01-01
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Series: | PPAR Research |
Online Access: | http://dx.doi.org/10.1155/2014/374075 |
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