Iron(III) edta-accelerated growth of gold/silver core/shell nanoparticles for wide-range colorimetric detection of hydrogen peroxide
Abstract As a naturally occurring reducing and oxidizing agent, hydrogen peroxide (H2O2) has a role in several biotic and abiotic processes. Hence, the onsite, precise, and rapid determination of H2O2 is crucial. Herein, we propose a method for colorimetric detection of H2O2 on the basis of hindered...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-02-01
|
| Series: | Scientific Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/s41598-025-88342-4 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1823862293630287872 |
|---|---|
| author | Mahdi Hemmati Amir Hossein Q. Selakjan Forough Ghasemi |
| author_facet | Mahdi Hemmati Amir Hossein Q. Selakjan Forough Ghasemi |
| author_sort | Mahdi Hemmati |
| collection | DOAJ |
| description | Abstract As a naturally occurring reducing and oxidizing agent, hydrogen peroxide (H2O2) has a role in several biotic and abiotic processes. Hence, the onsite, precise, and rapid determination of H2O2 is crucial. Herein, we propose a method for colorimetric detection of H2O2 on the basis of hindered formation of gold/silver core/shell nanoparticles. We used ascorbic acid (AA) as the electron donor to reduce silver ions (Ag+) to be shelled around gold nanoparticles and iron(III) edta as an accelerator reactant. Upon reduction of Ag+, owing to the formation of core/shell nanoparticles, the color of the system changes from pink to yellow/orange in the spherical nanoparticles and from pink to purple/blue/green/yellow/orange in the nanorods. The nanorods distinguished color in a rainbow manner for higher concentrations of H2O2, and spherical nanoparticles were critical in the sensitive detection of lower concentrations of H2O2. H2O2 scavenges AA electrons and therefore inhibits core/shell formation and, consequently, restrains the system’s spectral shift and color change. This characteristic was exploited to measure different concentrations of H2O2. Under well-optimized conditions, various concentrations of H2O2 ranging from 1.0 to 50 µΜ have shown an acceptable linear relationship with different colors and, with a limit of detection (LOD) of 230 nM. Furthermore, various real samples were examined to confirm the practicality of our developed probe. |
| format | Article |
| id | doaj-art-45120790c47b4fb6875ac658fafd71b3 |
| institution | Kabale University |
| issn | 2045-2322 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj-art-45120790c47b4fb6875ac658fafd71b32025-02-09T12:35:56ZengNature PortfolioScientific Reports2045-23222025-02-0115111210.1038/s41598-025-88342-4Iron(III) edta-accelerated growth of gold/silver core/shell nanoparticles for wide-range colorimetric detection of hydrogen peroxideMahdi Hemmati0Amir Hossein Q. Selakjan1Forough Ghasemi2Department of Nanotechnology, Agricultural Biotechnology Research Institute of Iran (ABRII), Agricultural Research, Education, and Extension Organization (AREEO)Department of Nanotechnology, Agricultural Biotechnology Research Institute of Iran (ABRII), Agricultural Research, Education, and Extension Organization (AREEO)Department of Nanotechnology, Agricultural Biotechnology Research Institute of Iran (ABRII), Agricultural Research, Education, and Extension Organization (AREEO)Abstract As a naturally occurring reducing and oxidizing agent, hydrogen peroxide (H2O2) has a role in several biotic and abiotic processes. Hence, the onsite, precise, and rapid determination of H2O2 is crucial. Herein, we propose a method for colorimetric detection of H2O2 on the basis of hindered formation of gold/silver core/shell nanoparticles. We used ascorbic acid (AA) as the electron donor to reduce silver ions (Ag+) to be shelled around gold nanoparticles and iron(III) edta as an accelerator reactant. Upon reduction of Ag+, owing to the formation of core/shell nanoparticles, the color of the system changes from pink to yellow/orange in the spherical nanoparticles and from pink to purple/blue/green/yellow/orange in the nanorods. The nanorods distinguished color in a rainbow manner for higher concentrations of H2O2, and spherical nanoparticles were critical in the sensitive detection of lower concentrations of H2O2. H2O2 scavenges AA electrons and therefore inhibits core/shell formation and, consequently, restrains the system’s spectral shift and color change. This characteristic was exploited to measure different concentrations of H2O2. Under well-optimized conditions, various concentrations of H2O2 ranging from 1.0 to 50 µΜ have shown an acceptable linear relationship with different colors and, with a limit of detection (LOD) of 230 nM. Furthermore, various real samples were examined to confirm the practicality of our developed probe.https://doi.org/10.1038/s41598-025-88342-4Hydrogen peroxide detectionIron(III) edta accelerator reactantCore/shell nanoparticles |
| spellingShingle | Mahdi Hemmati Amir Hossein Q. Selakjan Forough Ghasemi Iron(III) edta-accelerated growth of gold/silver core/shell nanoparticles for wide-range colorimetric detection of hydrogen peroxide Scientific Reports Hydrogen peroxide detection Iron(III) edta accelerator reactant Core/shell nanoparticles |
| title | Iron(III) edta-accelerated growth of gold/silver core/shell nanoparticles for wide-range colorimetric detection of hydrogen peroxide |
| title_full | Iron(III) edta-accelerated growth of gold/silver core/shell nanoparticles for wide-range colorimetric detection of hydrogen peroxide |
| title_fullStr | Iron(III) edta-accelerated growth of gold/silver core/shell nanoparticles for wide-range colorimetric detection of hydrogen peroxide |
| title_full_unstemmed | Iron(III) edta-accelerated growth of gold/silver core/shell nanoparticles for wide-range colorimetric detection of hydrogen peroxide |
| title_short | Iron(III) edta-accelerated growth of gold/silver core/shell nanoparticles for wide-range colorimetric detection of hydrogen peroxide |
| title_sort | iron iii edta accelerated growth of gold silver core shell nanoparticles for wide range colorimetric detection of hydrogen peroxide |
| topic | Hydrogen peroxide detection Iron(III) edta accelerator reactant Core/shell nanoparticles |
| url | https://doi.org/10.1038/s41598-025-88342-4 |
| work_keys_str_mv | AT mahdihemmati ironiiiedtaacceleratedgrowthofgoldsilvercoreshellnanoparticlesforwiderangecolorimetricdetectionofhydrogenperoxide AT amirhosseinqselakjan ironiiiedtaacceleratedgrowthofgoldsilvercoreshellnanoparticlesforwiderangecolorimetricdetectionofhydrogenperoxide AT foroughghasemi ironiiiedtaacceleratedgrowthofgoldsilvercoreshellnanoparticlesforwiderangecolorimetricdetectionofhydrogenperoxide |