Growth hormone receptor promotes osteosarcoma cell growth and metastases

Growth hormone receptor promotes osteosarcoma cell growth and metastases

Osteosarcoma (OS) is the primary bone malignancy in children and adolescents, with a high incidence of lung metastasis and poor prognosis. Here, we report that growth hormone receptor (GHR) is overexpressed in OS samples compared with osteofibrous dysplasia. We subsequently demonstrated that GHR kno...

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Bibliographic Details
Main Authors: Mo Cheng, Wending Huang, Weiluo Cai, Meng Fang, Yong Chen, Chunmeng Wang, Wangjun Yan
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:FEBS Open Bio
Subjects:
growth hormone receptor
metastasis
osteosarcoma
proliferation
tumor growth
Online Access:https://doi.org/10.1002/2211-5463.12761
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