Activity-dependent development of synaptic circuits mediates direction selectivity in an axis-specific manner

Activity-dependent development of synaptic circuits mediates direction selectivity in an axis-specific manner

Summary: The optokinetic reflex (OKR), which stabilizes images on the retina as a mouse navigates its environment, originates in direction-selective ganglion cells (DSGCs). A mouse model that lacks cholinergic retinal waves, the β2-nAChR-KO mouse, does not develop horizontal direction selectivity bu...

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Bibliographic Details
Main Authors: Karina Bistrong, Rachana Deven Somaiya, Eugene Y. Liang, Benjamin E. Smith, Marla B. Feller
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:Cell Reports
Subjects:
CP: Neuroscience
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124725006680
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