A brief review on microphthalmia and anophthalmia

Anophthalmia and microphthalmia are congenital eye abnormalities characterized by the absence or underdevelopment of one or both eyes, respectively. These conditions pose significant challenges to affected individuals, impacting both visual function and cosmetic appearance. The etiology of anophthal...

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Bibliographic Details
Main Authors: Jayasri Periyandavan, Mary Stephen
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-12-01
Series:Kerala Journal of Ophthalmology
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Online Access:https://journals.lww.com/10.4103/kjo.kjo_34_24
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Summary:Anophthalmia and microphthalmia are congenital eye abnormalities characterized by the absence or underdevelopment of one or both eyes, respectively. These conditions pose significant challenges to affected individuals, impacting both visual function and cosmetic appearance. The etiology of anophthalmia/microphthalmia is multifactorial, involving genetic, environmental, and developmental factors. Diagnosis typically relies on clinical examination and imaging studies, with prenatal detection becoming increasingly feasible through advanced ultrasound techniques. Surgical management forms the cornerstone of treatment, aiming to optimize orbital and ocular growth, enhance cosmetic outcomes, and maximize residual vision. Despite advancements in understanding and management, anophthalmia and microphthalmia remain major causes of childhood blindness, highlighting the ongoing need for research to elucidate underlying mechanisms and develop novel therapeutic strategies.
ISSN:0976-6677