Breast Mass and Lytic Bone Lesions: A Rare Presentation of Non-Hodgkin’s Lymphoma Arising in the Breast
Background. Primary breast lymphoma is a rare malignancy representing less than 1% of all tumors presenting in the breast. Case Presentation. A 55-year-old woman presented with altered mental status due to severe hypercalcemia and was found to have a large breast mass with lytic bone lesions in the...
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | Case Reports in Oncological Medicine |
| Online Access: | http://dx.doi.org/10.1155/2013/547171 |
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| author | Hira Ali Oladapo Yeku Daniel Giesler Ryan Campbell-Massa Faye Gao Ali Imran Amjad |
| author_facet | Hira Ali Oladapo Yeku Daniel Giesler Ryan Campbell-Massa Faye Gao Ali Imran Amjad |
| author_sort | Hira Ali |
| collection | DOAJ |
| description | Background. Primary breast lymphoma is a rare malignancy representing less than 1% of all tumors presenting in the breast. Case Presentation. A 55-year-old woman presented with altered mental status due to severe hypercalcemia and was found to have a large breast mass with lytic bone lesions in the calvarium of the skull. Biopsy of the mass revealed diffuse large B-cell lymphoma. Staging workup did not reveal any visceral organ or distant lymph node involvement. The patient’s bone marrow biopsy was positive for involvement with lymphoma. Interestingly, the patient also had a non quantifiable IgA kappa monoclonal protein in the serum. Conclusion. Here, we describe a common presentation in medical oncology, that is, a patient presenting as a clinically advanced breast tumor with hypercalcemia from lytic bone lesions. However, diagnostic workup led to the diagnosis of another common malignancy in an uncommon location, namely, diffuse large B-cell lymphoma arising in the breast. |
| format | Article |
| id | doaj-art-44ed09c55124430bbbd63fed6fb8f2e8 |
| institution | Kabale University |
| issn | 2090-6706 2090-6714 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Oncological Medicine |
| spelling | doaj-art-44ed09c55124430bbbd63fed6fb8f2e82025-02-03T06:12:31ZengWileyCase Reports in Oncological Medicine2090-67062090-67142013-01-01201310.1155/2013/547171547171Breast Mass and Lytic Bone Lesions: A Rare Presentation of Non-Hodgkin’s Lymphoma Arising in the BreastHira Ali0Oladapo Yeku1Daniel Giesler2Ryan Campbell-Massa3Faye Gao4Ali Imran Amjad5Division of General Internal Medicine, Department of Medicine, University of Pittsburgh Medical Centre, Pittsburgh, PA 15213, USADivision of General Internal Medicine, Department of Medicine, University of Pittsburgh Medical Centre, Pittsburgh, PA 15213, USADivision of General Internal Medicine, Department of Medicine, University of Pittsburgh Medical Centre, Pittsburgh, PA 15213, USADivision of General Internal Medicine, Department of Medicine, University of Pittsburgh Medical Centre, Pittsburgh, PA 15213, USADivision of Hematopathology, Department of Pathology, University of Pittsburgh Medical Centre, Pittsburgh, PA 15213, USADivision of Hematology/Oncology, Department of Medicine, University of Pittsburgh Medical Centre, Pittsburgh, PA 15232, USABackground. Primary breast lymphoma is a rare malignancy representing less than 1% of all tumors presenting in the breast. Case Presentation. A 55-year-old woman presented with altered mental status due to severe hypercalcemia and was found to have a large breast mass with lytic bone lesions in the calvarium of the skull. Biopsy of the mass revealed diffuse large B-cell lymphoma. Staging workup did not reveal any visceral organ or distant lymph node involvement. The patient’s bone marrow biopsy was positive for involvement with lymphoma. Interestingly, the patient also had a non quantifiable IgA kappa monoclonal protein in the serum. Conclusion. Here, we describe a common presentation in medical oncology, that is, a patient presenting as a clinically advanced breast tumor with hypercalcemia from lytic bone lesions. However, diagnostic workup led to the diagnosis of another common malignancy in an uncommon location, namely, diffuse large B-cell lymphoma arising in the breast.http://dx.doi.org/10.1155/2013/547171 |
| spellingShingle | Hira Ali Oladapo Yeku Daniel Giesler Ryan Campbell-Massa Faye Gao Ali Imran Amjad Breast Mass and Lytic Bone Lesions: A Rare Presentation of Non-Hodgkin’s Lymphoma Arising in the Breast Case Reports in Oncological Medicine |
| title | Breast Mass and Lytic Bone Lesions: A Rare Presentation of Non-Hodgkin’s Lymphoma Arising in the Breast |
| title_full | Breast Mass and Lytic Bone Lesions: A Rare Presentation of Non-Hodgkin’s Lymphoma Arising in the Breast |
| title_fullStr | Breast Mass and Lytic Bone Lesions: A Rare Presentation of Non-Hodgkin’s Lymphoma Arising in the Breast |
| title_full_unstemmed | Breast Mass and Lytic Bone Lesions: A Rare Presentation of Non-Hodgkin’s Lymphoma Arising in the Breast |
| title_short | Breast Mass and Lytic Bone Lesions: A Rare Presentation of Non-Hodgkin’s Lymphoma Arising in the Breast |
| title_sort | breast mass and lytic bone lesions a rare presentation of non hodgkin s lymphoma arising in the breast |
| url | http://dx.doi.org/10.1155/2013/547171 |
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