A personal sensing technology enabled service versus a digital psychoeducation control for primary care patients with depression and anxiety: a pilot randomized controlled trial
Abstract Background Technology-enabled services (TES; clinical services that include both technology-driven [e.g., personal sensing technologies] and person-powered support elements) may address gaps in depression and anxiety treatments in healthcare settings. The current study: (1) developed a TES...
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BMC
2024-11-01
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| Series: | BMC Psychiatry |
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| Online Access: | https://doi.org/10.1186/s12888-024-06284-z |
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| author | Colleen Stiles-Shields Karen M. Reyes Tanvi Lakhtakia Shannon R. Smith Olga E. Barnas Elizabeth L. Gray Charles J. Krause Kaylee P. Kruzan Mary J. Kwasny Zara Mir Sameer Panjwani Steven K. Rothschild Lisa Sánchez-Johnsen Nathan W. Winquist Emily G. Lattie Nicholas B. Allen Madhu Reddy David C. Mohr |
| author_facet | Colleen Stiles-Shields Karen M. Reyes Tanvi Lakhtakia Shannon R. Smith Olga E. Barnas Elizabeth L. Gray Charles J. Krause Kaylee P. Kruzan Mary J. Kwasny Zara Mir Sameer Panjwani Steven K. Rothschild Lisa Sánchez-Johnsen Nathan W. Winquist Emily G. Lattie Nicholas B. Allen Madhu Reddy David C. Mohr |
| author_sort | Colleen Stiles-Shields |
| collection | DOAJ |
| description | Abstract Background Technology-enabled services (TES; clinical services that include both technology-driven [e.g., personal sensing technologies] and person-powered support elements) may address gaps in depression and anxiety treatments in healthcare settings. The current study: (1) developed a TES tailored for Primary Care patients with depression and/or anxiety, and (2) conducted a pilot randomized controlled trial to assess the efficacy of the TES compared to a digital psychoeducation control app. Methods Participants were randomized to either: (1) TES: the “Vira” smartphone app (Ksana Health Inc.), informed by behavioral activation and using passive sensing technology to provide behavioral “insights” and target behaviors associated with mental health symptoms, alongside lay-provider coaching, or (2) Control: the Mood Education mobile app (ME), containing static psychoeducational resources designed to target mental health symptoms. Both apps collected usage data. Participants completed assessments on depression (PHQ-9), anxiety (GAD-7), health-related quality of life (PedsQL), and engagement (TWEETs) at baseline, mid-treatment (week 4), end-of-treatment (week 8), and post-treatment (week 12). Results Participants (N = 130) were randomized to receive either the TES (Vira; Mage= 30) or ME (Mage= 33). Linear mixed-effects models determined significant improvements in PHQ-9 and GAD-7 scores for participants across both conditions (ps < 0.001). There was no interactive effect of intervention and time for the PHQ-9 (p = .90) nor the GAD-7 (p = .49). Adjusting for baseline differences and randomization strata, TES participants reported a greater change in a quality of life rating of Physical Functioning (PedsQL) across time (p = .018). TES participants also reported higher levels of engagement and demonstrated higher app usage. However, adjusting for baseline symptom severity, neither app usage nor coach interaction frequency moderated outcomes (ps ≥ 0.2). Conclusions While the TES demonstrated superior engagement, improvements in depressive and anxious symptoms for both conditions speak to the potential benefit of both TES and low-intensity psychoeducation treatments in care settings. Future research is needed to better understand which patients might differentially benefit from TESs and broader personal sensing technologies over low-intensity treatments. Trial registration ClinicalTrials.gov NCT05406791. |
| format | Article |
| id | doaj-art-44e90c91c4fe4ee1915413b58973ae89 |
| institution | Kabale University |
| issn | 1471-244X |
| language | English |
| publishDate | 2024-11-01 |
| publisher | BMC |
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| series | BMC Psychiatry |
| spelling | doaj-art-44e90c91c4fe4ee1915413b58973ae892025-01-05T12:42:52ZengBMCBMC Psychiatry1471-244X2024-11-0124111510.1186/s12888-024-06284-zA personal sensing technology enabled service versus a digital psychoeducation control for primary care patients with depression and anxiety: a pilot randomized controlled trialColleen Stiles-Shields0Karen M. Reyes1Tanvi Lakhtakia2Shannon R. Smith3Olga E. Barnas4Elizabeth L. Gray5Charles J. Krause6Kaylee P. Kruzan7Mary J. Kwasny8Zara Mir9Sameer Panjwani10Steven K. Rothschild11Lisa Sánchez-Johnsen12Nathan W. Winquist13Emily G. Lattie14Nicholas B. Allen15Madhu Reddy16David C. Mohr17Institute for Juvenile Research, Department of Psychiatry, University of Illinois ChicagoDepartment of Psychiatry & Behavioral Sciences, RUSH University Medical CenterCenter for Behavioral Intervention Technologies, Northwestern UniversityCenter for Behavioral Intervention Technologies, Northwestern UniversityCenter for Behavioral Intervention Technologies, Northwestern UniversityDepartment of Preventive Medicine, Feinberg School of Medicine, Northwestern UniversityCenter for Behavioral Intervention Technologies, Northwestern UniversityCenter for Behavioral Intervention Technologies, Northwestern UniversityDepartment of Preventive Medicine, Feinberg School of Medicine, Northwestern UniversityCenter for Behavioral Intervention Technologies, Northwestern UniversityDepartment of Family and Preventive Medicine, RUSH University Medical CenterDepartment of Family and Preventive Medicine, RUSH University Medical CenterInstitute of Health and Equity, Department of Psychiatry & Behavioral Medicine, Surgery, and Family MedicineCenter for Behavioral Intervention Technologies, Northwestern UniversityDepartment of Medical Social Sciences, Feinberg School of Medicine, Northwestern UniversityDepartment of Psychology, University of Oregon, Ksana Health Inc.Department of Informatics, University of CaliforniaCenter for Behavioral Intervention Technologies, Northwestern UniversityAbstract Background Technology-enabled services (TES; clinical services that include both technology-driven [e.g., personal sensing technologies] and person-powered support elements) may address gaps in depression and anxiety treatments in healthcare settings. The current study: (1) developed a TES tailored for Primary Care patients with depression and/or anxiety, and (2) conducted a pilot randomized controlled trial to assess the efficacy of the TES compared to a digital psychoeducation control app. Methods Participants were randomized to either: (1) TES: the “Vira” smartphone app (Ksana Health Inc.), informed by behavioral activation and using passive sensing technology to provide behavioral “insights” and target behaviors associated with mental health symptoms, alongside lay-provider coaching, or (2) Control: the Mood Education mobile app (ME), containing static psychoeducational resources designed to target mental health symptoms. Both apps collected usage data. Participants completed assessments on depression (PHQ-9), anxiety (GAD-7), health-related quality of life (PedsQL), and engagement (TWEETs) at baseline, mid-treatment (week 4), end-of-treatment (week 8), and post-treatment (week 12). Results Participants (N = 130) were randomized to receive either the TES (Vira; Mage= 30) or ME (Mage= 33). Linear mixed-effects models determined significant improvements in PHQ-9 and GAD-7 scores for participants across both conditions (ps < 0.001). There was no interactive effect of intervention and time for the PHQ-9 (p = .90) nor the GAD-7 (p = .49). Adjusting for baseline differences and randomization strata, TES participants reported a greater change in a quality of life rating of Physical Functioning (PedsQL) across time (p = .018). TES participants also reported higher levels of engagement and demonstrated higher app usage. However, adjusting for baseline symptom severity, neither app usage nor coach interaction frequency moderated outcomes (ps ≥ 0.2). Conclusions While the TES demonstrated superior engagement, improvements in depressive and anxious symptoms for both conditions speak to the potential benefit of both TES and low-intensity psychoeducation treatments in care settings. Future research is needed to better understand which patients might differentially benefit from TESs and broader personal sensing technologies over low-intensity treatments. Trial registration ClinicalTrials.gov NCT05406791.https://doi.org/10.1186/s12888-024-06284-zTechnology-enabled servicePassive sensing technologyLow-intensity treatmentsDepressionAnxietyPrimary care |
| spellingShingle | Colleen Stiles-Shields Karen M. Reyes Tanvi Lakhtakia Shannon R. Smith Olga E. Barnas Elizabeth L. Gray Charles J. Krause Kaylee P. Kruzan Mary J. Kwasny Zara Mir Sameer Panjwani Steven K. Rothschild Lisa Sánchez-Johnsen Nathan W. Winquist Emily G. Lattie Nicholas B. Allen Madhu Reddy David C. Mohr A personal sensing technology enabled service versus a digital psychoeducation control for primary care patients with depression and anxiety: a pilot randomized controlled trial BMC Psychiatry Technology-enabled service Passive sensing technology Low-intensity treatments Depression Anxiety Primary care |
| title | A personal sensing technology enabled service versus a digital psychoeducation control for primary care patients with depression and anxiety: a pilot randomized controlled trial |
| title_full | A personal sensing technology enabled service versus a digital psychoeducation control for primary care patients with depression and anxiety: a pilot randomized controlled trial |
| title_fullStr | A personal sensing technology enabled service versus a digital psychoeducation control for primary care patients with depression and anxiety: a pilot randomized controlled trial |
| title_full_unstemmed | A personal sensing technology enabled service versus a digital psychoeducation control for primary care patients with depression and anxiety: a pilot randomized controlled trial |
| title_short | A personal sensing technology enabled service versus a digital psychoeducation control for primary care patients with depression and anxiety: a pilot randomized controlled trial |
| title_sort | personal sensing technology enabled service versus a digital psychoeducation control for primary care patients with depression and anxiety a pilot randomized controlled trial |
| topic | Technology-enabled service Passive sensing technology Low-intensity treatments Depression Anxiety Primary care |
| url | https://doi.org/10.1186/s12888-024-06284-z |
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