Analysis and Prediction of Perfluorane Adsorption of Drugs on the Basis of the Physicochemical Properties of Ligands

Analysis and Prediction of Perfluorane Adsorption of Drugs on the Basis of the Physicochemical Properties of Ligands

The relationships between drug affinity constant (Kag) for the particles of perfluorane nanoemulsion and physicochemical properties of ligands were studied by correlation and multiple regression analyses. The following parameters were applied: lipophilicity (LogP), molecular weight (MW), topological...

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Bibliographic Details
Main Authors: N. N. Pshenkina, G. A. Sofronov
Format: Article
Language:English
Published: Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia 2011-06-01
Series:Общая реаниматология
Subjects:
perfluorane
drugs
binding
prediction.
Online Access:https://www.reanimatology.com/rmt/article/view/295
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