Atypical presentation of primary Ewing's sarcoma

Ewing's sarcoma is the second most common bone tumor in children and adolescents. Its annual incidence is 0.6/million total population worldwide, and in some populations in India, its incidence can account for 15%–19.4% of the primary bone tumors. Ewing's sarcoma is a highly malignant roun...

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Main Authors: Nancy V Jeniffer, Arpitha Panduranga, B P Karunakara
Format: Article
Language:English
Published: Thieme Medical and Scientific Publishers Pvt. Ltd. 2018-01-01
Series:Indian Journal of Medical and Paediatric Oncology
Subjects:
Online Access:http://www.ijmpo.org/article.asp?issn=0971-5851;year=2018;volume=39;issue=3;spage=398;epage=399;aulast=Jeniffer
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author Nancy V Jeniffer
Arpitha Panduranga
B P Karunakara
author_facet Nancy V Jeniffer
Arpitha Panduranga
B P Karunakara
author_sort Nancy V Jeniffer
collection DOAJ
description Ewing's sarcoma is the second most common bone tumor in children and adolescents. Its annual incidence is 0.6/million total population worldwide, and in some populations in India, its incidence can account for 15%–19.4% of the primary bone tumors. Ewing's sarcoma is a highly malignant round cell tumor, affecting the metadiaphyseal and the diaphyseal regions of the long bones. Spine involvement, as a primary focus in Ewings sarcoma is uncommon, but when present, usually affects the sacrum. Origin from non sacral region is extremely rare. We report a case of acute onset of paraplegia progressing to quadriplegia in a child with metastatic involvement of the spine, primary focus being the nonsacral spine which is inherently challenging to an early diagnosis. Ewing's sarcoma though has improved survival with chemotherapy and radiotherapy, primary spine focus has poor prognosis.
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spelling doaj-art-44da3672dfa648b39aced455a2f28dcf2025-08-20T03:09:41ZengThieme Medical and Scientific Publishers Pvt. Ltd.Indian Journal of Medical and Paediatric Oncology0971-58512018-01-0139339839910.4103/ijmpo.ijmpo_71_17Atypical presentation of primary Ewing's sarcomaNancy V JenifferArpitha PandurangaB P KarunakaraEwing's sarcoma is the second most common bone tumor in children and adolescents. Its annual incidence is 0.6/million total population worldwide, and in some populations in India, its incidence can account for 15%–19.4% of the primary bone tumors. Ewing's sarcoma is a highly malignant round cell tumor, affecting the metadiaphyseal and the diaphyseal regions of the long bones. Spine involvement, as a primary focus in Ewings sarcoma is uncommon, but when present, usually affects the sacrum. Origin from non sacral region is extremely rare. We report a case of acute onset of paraplegia progressing to quadriplegia in a child with metastatic involvement of the spine, primary focus being the nonsacral spine which is inherently challenging to an early diagnosis. Ewing's sarcoma though has improved survival with chemotherapy and radiotherapy, primary spine focus has poor prognosis.http://www.ijmpo.org/article.asp?issn=0971-5851;year=2018;volume=39;issue=3;spage=398;epage=399;aulast=JenifferAcute onset paraplegiacord compressionEwing's sarcomamalignant bone tumors of childhoodspine involvement
spellingShingle Nancy V Jeniffer
Arpitha Panduranga
B P Karunakara
Atypical presentation of primary Ewing's sarcoma
Indian Journal of Medical and Paediatric Oncology
Acute onset paraplegia
cord compression
Ewing's sarcoma
malignant bone tumors of childhood
spine involvement
title Atypical presentation of primary Ewing's sarcoma
title_full Atypical presentation of primary Ewing's sarcoma
title_fullStr Atypical presentation of primary Ewing's sarcoma
title_full_unstemmed Atypical presentation of primary Ewing's sarcoma
title_short Atypical presentation of primary Ewing's sarcoma
title_sort atypical presentation of primary ewing s sarcoma
topic Acute onset paraplegia
cord compression
Ewing's sarcoma
malignant bone tumors of childhood
spine involvement
url http://www.ijmpo.org/article.asp?issn=0971-5851;year=2018;volume=39;issue=3;spage=398;epage=399;aulast=Jeniffer
work_keys_str_mv AT nancyvjeniffer atypicalpresentationofprimaryewingssarcoma
AT arpithapanduranga atypicalpresentationofprimaryewingssarcoma
AT bpkarunakara atypicalpresentationofprimaryewingssarcoma