Case report: A case of esophageal small cell carcinoma misdiagnosed as leiomyoma
Primary esophageal small cell carcinoma (PESC) is a rare, extremely aggressive malignancy characterized by rapid growth, early metastasis, and poor prognosis. This study presents a case of early-stage PESC that was initially misdiagnosed as an esophageal leiomyoma, which was observed as a submucosal...
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Frontiers Media S.A.
2024-12-01
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| Series: | Frontiers in Medicine |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fmed.2024.1489207/full |
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| author | Junjun Yan Junjun Yan Xifeng Xiao |
| author_facet | Junjun Yan Junjun Yan Xifeng Xiao |
| author_sort | Junjun Yan |
| collection | DOAJ |
| description | Primary esophageal small cell carcinoma (PESC) is a rare, extremely aggressive malignancy characterized by rapid growth, early metastasis, and poor prognosis. This study presents a case of early-stage PESC that was initially misdiagnosed as an esophageal leiomyoma, which was observed as a submucosal tumor during gastroscopy. The patient subsequently underwent endoscopic submucosal dissection (ESD), which successfully achieved complete tumor resection. Histopathological analysis later confirmed the diagnosis of small cell carcinoma. Subsequent treatments were recommended; however, the patient declined these options and developed systemic metastases 16 months later, indicating progression to advanced disease and a poor prognosis. This case underscores the imperative to consider PESC in the differential diagnosis of submucosal esophageal lesions, especially when clinical suspicion is elevated, despite its rarity. Additionally, it highlights the challenges associated with the diagnosis and management of submucosal PESC and emphasizes the crucial role of early diagnosis in enhancing patient prognosis and survival rates. |
| format | Article |
| id | doaj-art-44d2e04fb734489eae2cd070ace5d433 |
| institution | OA Journals |
| issn | 2296-858X |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Medicine |
| spelling | doaj-art-44d2e04fb734489eae2cd070ace5d4332025-08-20T02:19:54ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2024-12-011110.3389/fmed.2024.14892071489207Case report: A case of esophageal small cell carcinoma misdiagnosed as leiomyomaJunjun Yan0Junjun Yan1Xifeng Xiao2Department of Gastroenterology, Jiujiang City Key Laboratory of Cell Therapy, The First Hospital of Jiujiang City, Jiujiang, ChinaDepartment of Gastroenterology, Jiangxi Provincial Key Laboratory of Digestive Diseases, Jiangxi Clinical Research Center for Gastroenterology, Digestive Disease Hospital, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, ChinaDepartment of Gastroenterology, Jiujiang City Key Laboratory of Cell Therapy, The First Hospital of Jiujiang City, Jiujiang, ChinaPrimary esophageal small cell carcinoma (PESC) is a rare, extremely aggressive malignancy characterized by rapid growth, early metastasis, and poor prognosis. This study presents a case of early-stage PESC that was initially misdiagnosed as an esophageal leiomyoma, which was observed as a submucosal tumor during gastroscopy. The patient subsequently underwent endoscopic submucosal dissection (ESD), which successfully achieved complete tumor resection. Histopathological analysis later confirmed the diagnosis of small cell carcinoma. Subsequent treatments were recommended; however, the patient declined these options and developed systemic metastases 16 months later, indicating progression to advanced disease and a poor prognosis. This case underscores the imperative to consider PESC in the differential diagnosis of submucosal esophageal lesions, especially when clinical suspicion is elevated, despite its rarity. Additionally, it highlights the challenges associated with the diagnosis and management of submucosal PESC and emphasizes the crucial role of early diagnosis in enhancing patient prognosis and survival rates.https://www.frontiersin.org/articles/10.3389/fmed.2024.1489207/fullprimary esophageal small cell carcinomasubmucosal tumorearly interventionendoscopic submucosal dissectioncase report |
| spellingShingle | Junjun Yan Junjun Yan Xifeng Xiao Case report: A case of esophageal small cell carcinoma misdiagnosed as leiomyoma Frontiers in Medicine primary esophageal small cell carcinoma submucosal tumor early intervention endoscopic submucosal dissection case report |
| title | Case report: A case of esophageal small cell carcinoma misdiagnosed as leiomyoma |
| title_full | Case report: A case of esophageal small cell carcinoma misdiagnosed as leiomyoma |
| title_fullStr | Case report: A case of esophageal small cell carcinoma misdiagnosed as leiomyoma |
| title_full_unstemmed | Case report: A case of esophageal small cell carcinoma misdiagnosed as leiomyoma |
| title_short | Case report: A case of esophageal small cell carcinoma misdiagnosed as leiomyoma |
| title_sort | case report a case of esophageal small cell carcinoma misdiagnosed as leiomyoma |
| topic | primary esophageal small cell carcinoma submucosal tumor early intervention endoscopic submucosal dissection case report |
| url | https://www.frontiersin.org/articles/10.3389/fmed.2024.1489207/full |
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