Heavy chain deposition disease in a case of clear cell renal cell carcinoma- A jack in the box

Renal cell carcinoma (RCC) is the most common subtype of adult renal tumors, and its detection rate in the early stages has been increased in the dawn of advanced imaging modalities. Nephrectomy is the mainstay of treatment; determination of tumor category and staging is the primary concern of oncop...

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Main Authors: Abhishek Kumar, Arpita Roychowdhury, Moumita Sengupta, Keya Basu, Anila Abraham, Uttara Chatterjee, Sriranjan Mukherjee
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2023-07-01
Series:Indian Journal of Pathology and Microbiology
Subjects:
Online Access:https://journals.lww.com/10.4103/ijpm.ijpm_397_21
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author Abhishek Kumar
Arpita Roychowdhury
Moumita Sengupta
Keya Basu
Anila Abraham
Uttara Chatterjee
Sriranjan Mukherjee
author_facet Abhishek Kumar
Arpita Roychowdhury
Moumita Sengupta
Keya Basu
Anila Abraham
Uttara Chatterjee
Sriranjan Mukherjee
author_sort Abhishek Kumar
collection DOAJ
description Renal cell carcinoma (RCC) is the most common subtype of adult renal tumors, and its detection rate in the early stages has been increased in the dawn of advanced imaging modalities. Nephrectomy is the mainstay of treatment; determination of tumor category and staging is the primary concern of oncopathologists. Non-neoplastic renal parenchyma is overlooked majority of times and thus misses the opportunity to detect concomitant medical renal diseases which also predict the renal outcome in the postoperative era. Although any kind of glomerular or extraglomerular pathology may be encountered, vascular changes in the form of arterionephrosclerosis are the commonest one. Here, we take the opportunity to report an unusual association of heavy chain deposition disease (HCDD) with clear cell subtypes of renal cell carcinoma in a 48-year-old male of Indian ethnicity.
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institution Kabale University
issn 0377-4929
language English
publishDate 2023-07-01
publisher Wolters Kluwer Medknow Publications
record_format Article
series Indian Journal of Pathology and Microbiology
spelling doaj-art-44d18233244041b8b33c6538319ecb3a2025-02-07T13:32:43ZengWolters Kluwer Medknow PublicationsIndian Journal of Pathology and Microbiology0377-49292023-07-0166358759010.4103/ijpm.ijpm_397_21Heavy chain deposition disease in a case of clear cell renal cell carcinoma- A jack in the boxAbhishek KumarArpita RoychowdhuryMoumita SenguptaKeya BasuAnila AbrahamUttara ChatterjeeSriranjan MukherjeeRenal cell carcinoma (RCC) is the most common subtype of adult renal tumors, and its detection rate in the early stages has been increased in the dawn of advanced imaging modalities. Nephrectomy is the mainstay of treatment; determination of tumor category and staging is the primary concern of oncopathologists. Non-neoplastic renal parenchyma is overlooked majority of times and thus misses the opportunity to detect concomitant medical renal diseases which also predict the renal outcome in the postoperative era. Although any kind of glomerular or extraglomerular pathology may be encountered, vascular changes in the form of arterionephrosclerosis are the commonest one. Here, we take the opportunity to report an unusual association of heavy chain deposition disease (HCDD) with clear cell subtypes of renal cell carcinoma in a 48-year-old male of Indian ethnicity.https://journals.lww.com/10.4103/ijpm.ijpm_397_21heavy chain deposition diseasemedical renal diseaserenal cell carcinoma
spellingShingle Abhishek Kumar
Arpita Roychowdhury
Moumita Sengupta
Keya Basu
Anila Abraham
Uttara Chatterjee
Sriranjan Mukherjee
Heavy chain deposition disease in a case of clear cell renal cell carcinoma- A jack in the box
Indian Journal of Pathology and Microbiology
heavy chain deposition disease
medical renal disease
renal cell carcinoma
title Heavy chain deposition disease in a case of clear cell renal cell carcinoma- A jack in the box
title_full Heavy chain deposition disease in a case of clear cell renal cell carcinoma- A jack in the box
title_fullStr Heavy chain deposition disease in a case of clear cell renal cell carcinoma- A jack in the box
title_full_unstemmed Heavy chain deposition disease in a case of clear cell renal cell carcinoma- A jack in the box
title_short Heavy chain deposition disease in a case of clear cell renal cell carcinoma- A jack in the box
title_sort heavy chain deposition disease in a case of clear cell renal cell carcinoma a jack in the box
topic heavy chain deposition disease
medical renal disease
renal cell carcinoma
url https://journals.lww.com/10.4103/ijpm.ijpm_397_21
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