Impact of free provision of disinfectant wipes combined with bundle management on the prevention of multi-drug resistant organism infections in the respiratory and intensive care unit
ObjectiveTo explore the role of free provision of disinfectant wipes combined with bundle management in preventing Multi-Drug Resistant Organism (MDRO) infections in the Respiratory and Intensive Care Unit (RICU).MethodsThis study included patients admitted to the RICU between January 2022 and June...
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Frontiers Media S.A.
2025-07-01
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| Series: | Frontiers in Cellular and Infection Microbiology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fcimb.2025.1581545/full |
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| author | Yu-Dan Wang Jian-Hong Liang Xie-Nan Gao Li-Li Ma Shen-Shen Huang Yong-Mei Zhang |
| author_facet | Yu-Dan Wang Jian-Hong Liang Xie-Nan Gao Li-Li Ma Shen-Shen Huang Yong-Mei Zhang |
| author_sort | Yu-Dan Wang |
| collection | DOAJ |
| description | ObjectiveTo explore the role of free provision of disinfectant wipes combined with bundle management in preventing Multi-Drug Resistant Organism (MDRO) infections in the Respiratory and Intensive Care Unit (RICU).MethodsThis study included patients admitted to the RICU between January 2022 and June 2023 (control group) and from July 2023 to June 2024 (intervention group), all of whom met the inclusion criteria. The control group received standard bundle management measures, while the intervention group received unlimited use of disinfectant wipes combined with bundle management. The MDRO discovery rates and hospital-acquired infection incidence rates were compared between the two groups to assess the impact of free disinfectant wipe provision on MDRO infection prevention in the RICU.ResultsThere were no significant differences between the two groups in terms of patient age and baseline characteristics, except for Sex and the proportion of patients with chronic respiratory diseases. Notably, the MDRO discovery rate, MDRO infection rate, and hospital-acquired infection incidence were all significantly lower in the intervention group compared to the control group (MDRO discovery rate: 35.2% vs 45.9%, P<0.001; MDRO infection rate: 0.8% vs 3.5%, P = 0.003; hospital-acquired infection rate: 1.5% vs 3.52%, P=0.030). However, the intervention group had more percentage of patients receiving mechanical ventilation and longer ICU stay (P < 0.05). Furthermore, in-hospital mortality was lower in the intervention group (19.5% vs 13.5%, P < 0.05).ConclusionThe combined intervention of unlimited use of disinfectant wipes with bundle management significantly reduced MDRO hospital-acquired infection rates and in-hospital mortality in the RICU, demonstrating its effectiveness in infection prevention. |
| format | Article |
| id | doaj-art-44c0caad87f04ba088ac0061e1f94cf5 |
| institution | Kabale University |
| issn | 2235-2988 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Cellular and Infection Microbiology |
| spelling | doaj-art-44c0caad87f04ba088ac0061e1f94cf52025-08-20T03:33:43ZengFrontiers Media S.A.Frontiers in Cellular and Infection Microbiology2235-29882025-07-011510.3389/fcimb.2025.15815451581545Impact of free provision of disinfectant wipes combined with bundle management on the prevention of multi-drug resistant organism infections in the respiratory and intensive care unitYu-Dan Wang0Jian-Hong Liang1Xie-Nan Gao2Li-Li Ma3Shen-Shen Huang4Yong-Mei Zhang5Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital, and College of Clinical Medicine of Henan University of Science and Technology, Luoyang, ChinaDepartment of Infection Control, The First Affiliated Hospital, and College of Clinical Medicine of Henan University of Science and Technology, Luoyang, ChinaDepartment of Ophthalmology, The Yiluo Hospital of Luoyang, The Teaching Hospital of Henan University of Science and Technology, Luoyang, ChinaDepartment of Respiratory and Critical Care Medicine, The First Affiliated Hospital, and College of Clinical Medicine of Henan University of Science and Technology, Luoyang, ChinaDepartment of Respiratory and Critical Care Medicine, The First Affiliated Hospital, and College of Clinical Medicine of Henan University of Science and Technology, Luoyang, ChinaDepartment of Respiratory and Critical Care Medicine, The First Affiliated Hospital, and College of Clinical Medicine of Henan University of Science and Technology, Luoyang, ChinaObjectiveTo explore the role of free provision of disinfectant wipes combined with bundle management in preventing Multi-Drug Resistant Organism (MDRO) infections in the Respiratory and Intensive Care Unit (RICU).MethodsThis study included patients admitted to the RICU between January 2022 and June 2023 (control group) and from July 2023 to June 2024 (intervention group), all of whom met the inclusion criteria. The control group received standard bundle management measures, while the intervention group received unlimited use of disinfectant wipes combined with bundle management. The MDRO discovery rates and hospital-acquired infection incidence rates were compared between the two groups to assess the impact of free disinfectant wipe provision on MDRO infection prevention in the RICU.ResultsThere were no significant differences between the two groups in terms of patient age and baseline characteristics, except for Sex and the proportion of patients with chronic respiratory diseases. Notably, the MDRO discovery rate, MDRO infection rate, and hospital-acquired infection incidence were all significantly lower in the intervention group compared to the control group (MDRO discovery rate: 35.2% vs 45.9%, P<0.001; MDRO infection rate: 0.8% vs 3.5%, P = 0.003; hospital-acquired infection rate: 1.5% vs 3.52%, P=0.030). However, the intervention group had more percentage of patients receiving mechanical ventilation and longer ICU stay (P < 0.05). Furthermore, in-hospital mortality was lower in the intervention group (19.5% vs 13.5%, P < 0.05).ConclusionThe combined intervention of unlimited use of disinfectant wipes with bundle management significantly reduced MDRO hospital-acquired infection rates and in-hospital mortality in the RICU, demonstrating its effectiveness in infection prevention.https://www.frontiersin.org/articles/10.3389/fcimb.2025.1581545/fullrespiratory and intensive care unitmulti-drug resistant organismsdisinfectant wipesbundle management measuresprevention |
| spellingShingle | Yu-Dan Wang Jian-Hong Liang Xie-Nan Gao Li-Li Ma Shen-Shen Huang Yong-Mei Zhang Impact of free provision of disinfectant wipes combined with bundle management on the prevention of multi-drug resistant organism infections in the respiratory and intensive care unit Frontiers in Cellular and Infection Microbiology respiratory and intensive care unit multi-drug resistant organisms disinfectant wipes bundle management measures prevention |
| title | Impact of free provision of disinfectant wipes combined with bundle management on the prevention of multi-drug resistant organism infections in the respiratory and intensive care unit |
| title_full | Impact of free provision of disinfectant wipes combined with bundle management on the prevention of multi-drug resistant organism infections in the respiratory and intensive care unit |
| title_fullStr | Impact of free provision of disinfectant wipes combined with bundle management on the prevention of multi-drug resistant organism infections in the respiratory and intensive care unit |
| title_full_unstemmed | Impact of free provision of disinfectant wipes combined with bundle management on the prevention of multi-drug resistant organism infections in the respiratory and intensive care unit |
| title_short | Impact of free provision of disinfectant wipes combined with bundle management on the prevention of multi-drug resistant organism infections in the respiratory and intensive care unit |
| title_sort | impact of free provision of disinfectant wipes combined with bundle management on the prevention of multi drug resistant organism infections in the respiratory and intensive care unit |
| topic | respiratory and intensive care unit multi-drug resistant organisms disinfectant wipes bundle management measures prevention |
| url | https://www.frontiersin.org/articles/10.3389/fcimb.2025.1581545/full |
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