Visibility of esophageal squamous cell carcinoma under iodine staining on texture and color enhancement imaging
Abstract Objective Iodine staining on white light imaging (WLI) is the gold standard for detecting and demarcating esophageal squamous cell carcinoma (ESCC). We examined the effects of texture and color enhancement imaging (TXI) on improving the endoscopic visibility of ESCC under iodine staining. M...
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Wiley
2025-04-01
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| Online Access: | https://doi.org/10.1002/deo2.370 |
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| author | Tsunetaka Kato Takuto Hikichi Jun Nakamura Minami Hashimoto Ryoichiro Kobashi Takumi Yanagita Tadayuki Takagi Rei Suzuki Mitsuru Sugimoto Hiroyuki Asama Yuki Sato Yasuo Shioya Masao Kobayakawa Hiromasa Ohira |
| author_facet | Tsunetaka Kato Takuto Hikichi Jun Nakamura Minami Hashimoto Ryoichiro Kobashi Takumi Yanagita Tadayuki Takagi Rei Suzuki Mitsuru Sugimoto Hiroyuki Asama Yuki Sato Yasuo Shioya Masao Kobayakawa Hiromasa Ohira |
| author_sort | Tsunetaka Kato |
| collection | DOAJ |
| description | Abstract Objective Iodine staining on white light imaging (WLI) is the gold standard for detecting and demarcating esophageal squamous cell carcinoma (ESCC). We examined the effects of texture and color enhancement imaging (TXI) on improving the endoscopic visibility of ESCC under iodine staining. Methods Twenty ESCC lesions that underwent endoscopic submucosal dissection were retrospectively included. The color difference between ESCC and the surrounding mucosa (ΔEe) on WLI, TXI, and narrow‐band imaging was assessed, and ΔEe under 1% iodine staining on WLI and TXI. Furthermore, the visibility grade determined by endoscopists was evaluated on each imaging. Result The median ΔEe was greater on TXI than on WLI (14.53 vs. 10.71, respectively; p < 0.005). Moreover, the median ΔEe on TXI under iodine staining was greater than the median ΔEe on TXI and narrow‐band imaging (39.20 vs. 14.53 vs. 16.42, respectively; p < 0.005 for both). A positive correlation in ΔEe under iodine staining was found between TXI and WLI (correlation coefficient = 0.61, p < 0.01). Moreover, ΔEe under iodine staining on TXI in each lesion was greater than the corresponding ΔEe on WLI. The visibility grade assessed by endoscopists on TXI was also significantly greater than that on WLI under iodine staining (p < 0.01). Conclusions The visibility of ESCC after iodine staining was greater on TXI than on WLI. |
| format | Article |
| id | doaj-art-44bb60e0c76a4efb9bdf310fd7e434ba |
| institution | DOAJ |
| issn | 2692-4609 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | Wiley |
| record_format | Article |
| series | DEN Open |
| spelling | doaj-art-44bb60e0c76a4efb9bdf310fd7e434ba2025-08-20T03:13:36ZengWileyDEN Open2692-46092025-04-0151n/an/a10.1002/deo2.370Visibility of esophageal squamous cell carcinoma under iodine staining on texture and color enhancement imagingTsunetaka Kato0Takuto Hikichi1Jun Nakamura2Minami Hashimoto3Ryoichiro Kobashi4Takumi Yanagita5Tadayuki Takagi6Rei Suzuki7Mitsuru Sugimoto8Hiroyuki Asama9Yuki Sato10Yasuo Shioya11Masao Kobayakawa12Hiromasa Ohira13Department of Endoscopy Fukushima Medical University Hospital Fukushima JapanDepartment of Endoscopy Fukushima Medical University Hospital Fukushima JapanDepartment of Endoscopy Fukushima Medical University Hospital Fukushima JapanDepartment of Endoscopy Fukushima Medical University Hospital Fukushima JapanDepartment of Endoscopy Fukushima Medical University Hospital Fukushima JapanDepartment of Endoscopy Fukushima Medical University Hospital Fukushima JapanDepartment of Gastroenterology Fukushima Medical University School of Medicine Fukushima JapanDepartment of Gastroenterology Fukushima Medical University School of Medicine Fukushima JapanDepartment of Gastroenterology Fukushima Medical University School of Medicine Fukushima JapanDepartment of Gastroenterology Fukushima Medical University School of Medicine Fukushima JapanDepartment of Gastroenterology Fukushima Medical University School of Medicine Fukushima JapanDepartment of Gastroenterology Fukushima Medical University School of Medicine Fukushima JapanDepartment of Endoscopy Fukushima Medical University Hospital Fukushima JapanDepartment of Gastroenterology Fukushima Medical University School of Medicine Fukushima JapanAbstract Objective Iodine staining on white light imaging (WLI) is the gold standard for detecting and demarcating esophageal squamous cell carcinoma (ESCC). We examined the effects of texture and color enhancement imaging (TXI) on improving the endoscopic visibility of ESCC under iodine staining. Methods Twenty ESCC lesions that underwent endoscopic submucosal dissection were retrospectively included. The color difference between ESCC and the surrounding mucosa (ΔEe) on WLI, TXI, and narrow‐band imaging was assessed, and ΔEe under 1% iodine staining on WLI and TXI. Furthermore, the visibility grade determined by endoscopists was evaluated on each imaging. Result The median ΔEe was greater on TXI than on WLI (14.53 vs. 10.71, respectively; p < 0.005). Moreover, the median ΔEe on TXI under iodine staining was greater than the median ΔEe on TXI and narrow‐band imaging (39.20 vs. 14.53 vs. 16.42, respectively; p < 0.005 for both). A positive correlation in ΔEe under iodine staining was found between TXI and WLI (correlation coefficient = 0.61, p < 0.01). Moreover, ΔEe under iodine staining on TXI in each lesion was greater than the corresponding ΔEe on WLI. The visibility grade assessed by endoscopists on TXI was also significantly greater than that on WLI under iodine staining (p < 0.01). Conclusions The visibility of ESCC after iodine staining was greater on TXI than on WLI.https://doi.org/10.1002/deo2.370color differenceendoscopic diagnosisesophageal squamous cell carcinomaiodine stainingtexture and color enhancement imaging |
| spellingShingle | Tsunetaka Kato Takuto Hikichi Jun Nakamura Minami Hashimoto Ryoichiro Kobashi Takumi Yanagita Tadayuki Takagi Rei Suzuki Mitsuru Sugimoto Hiroyuki Asama Yuki Sato Yasuo Shioya Masao Kobayakawa Hiromasa Ohira Visibility of esophageal squamous cell carcinoma under iodine staining on texture and color enhancement imaging DEN Open color difference endoscopic diagnosis esophageal squamous cell carcinoma iodine staining texture and color enhancement imaging |
| title | Visibility of esophageal squamous cell carcinoma under iodine staining on texture and color enhancement imaging |
| title_full | Visibility of esophageal squamous cell carcinoma under iodine staining on texture and color enhancement imaging |
| title_fullStr | Visibility of esophageal squamous cell carcinoma under iodine staining on texture and color enhancement imaging |
| title_full_unstemmed | Visibility of esophageal squamous cell carcinoma under iodine staining on texture and color enhancement imaging |
| title_short | Visibility of esophageal squamous cell carcinoma under iodine staining on texture and color enhancement imaging |
| title_sort | visibility of esophageal squamous cell carcinoma under iodine staining on texture and color enhancement imaging |
| topic | color difference endoscopic diagnosis esophageal squamous cell carcinoma iodine staining texture and color enhancement imaging |
| url | https://doi.org/10.1002/deo2.370 |
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