EML4‐ALK‐Positive Ovarian Cancer With Intracranial Metastasis Responds to Lorlatinib: A Case Report and Literature Review

EML4‐ALK‐Positive Ovarian Cancer With Intracranial Metastasis Responds to Lorlatinib: A Case Report and Literature Review

ABSTRACT We report a case showing that lorlatinib is effective in treating EML4‐ALK‐positive low‐grade serous ovarian cancer (LGSO) with intracranial metastasis. This may be the first clinical evidence of LGSO benefit from ALK inhibitors, to provide evidence for the use of ALK inhibitors in more ova...

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Bibliographic Details
Main Authors: Qiongqian Li, Tongze Cai, Xiaoming Zheng, Shunrong Zhang, Chanjuan Li, Huang Tang, Zhiyong Yu, Jianlong Zhou
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Clinical Case Reports
Subjects:
EML4‐ALK fusion gene
intracranial metastasis
lorlatinib
ovarian cancer
Online Access:https://doi.org/10.1002/ccr3.70043
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