The study of the effect of virtual reality technology combined with sports games on improving cognitive function in patients with brain injury: a meta analysis of randomized controlled trials

BackgroundBrain injury is a major public health issue causing cognitive impairment. Key types include traumatic, ischemic, neurological, infectious, metabolic injuries, and stroke. As populations age, brain injury rates rise, making effective cognitive rehabilitation methods increasingly urgent. Vir...

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Main Authors: Yuze Zhang, Haojie Li, Hong Xiao
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Neurology
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Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2025.1579909/full
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author Yuze Zhang
Yuze Zhang
Haojie Li
Hong Xiao
author_facet Yuze Zhang
Yuze Zhang
Haojie Li
Hong Xiao
author_sort Yuze Zhang
collection DOAJ
description BackgroundBrain injury is a major public health issue causing cognitive impairment. Key types include traumatic, ischemic, neurological, infectious, metabolic injuries, and stroke. As populations age, brain injury rates rise, making effective cognitive rehabilitation methods increasingly urgent. Virtual reality sports games, blending immersion and training, offer a new rehab solution.MethodsFirstly, we registered in the International Prospective Systematic Review Registry (PROSPERO) website. A total of 12 randomized controlled trials were included in this Meta-analysis. Data were analyzed by Meta-analysis using the random effects model in State statistical software. The primary outcome indicator of the study was cognitive function.ResultsThis study included 12 RCTs with 540 participants to evaluate the impact of virtual reality exercise on cognitive function in brain-injured patients. The analysis revealed significant cognitive improvement with an SMD of 0.88 (95% CI: 0.59, 1.17), p = 0.019, and I2 = 51.9% using a random effects model. Sensitivity analysis confirmed robust findings with no significant single study effects. Symmetric funnel plots indicated no publication bias. These results support virtual reality as an effective cognitive intervention for brain-injured patients.ConclusionVirtual reality (VR) sports games significantly enhanced cognitive function, coordination, and reaction speed in brain-injured patients, thereby boosting their learning motivation and engagement.Systematic Review Registrationhttps://www.crd.york.ac.uk/PROSPERO/, identifier CRD42024581533.
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publishDate 2025-05-01
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spelling doaj-art-44b1f3e3d4584bc2bfed4c5f8595bf6c2025-08-20T01:49:20ZengFrontiers Media S.A.Frontiers in Neurology1664-22952025-05-011610.3389/fneur.2025.15799091579909The study of the effect of virtual reality technology combined with sports games on improving cognitive function in patients with brain injury: a meta analysis of randomized controlled trialsYuze Zhang0Yuze Zhang1Haojie Li2Hong Xiao3Department of Martial Arts and Ethnic Traditions, Henan Sport University, Zhengzhou, ChinaSchool of Physical Education, Yunnan Normal University, Yunnan, ChinaSchool of Exercise and Health, Shanghai University of Sport, Shanghai, ChinaDepartment of Martial Arts and Ethnic Traditions, Henan Sport University, Zhengzhou, ChinaBackgroundBrain injury is a major public health issue causing cognitive impairment. Key types include traumatic, ischemic, neurological, infectious, metabolic injuries, and stroke. As populations age, brain injury rates rise, making effective cognitive rehabilitation methods increasingly urgent. Virtual reality sports games, blending immersion and training, offer a new rehab solution.MethodsFirstly, we registered in the International Prospective Systematic Review Registry (PROSPERO) website. A total of 12 randomized controlled trials were included in this Meta-analysis. Data were analyzed by Meta-analysis using the random effects model in State statistical software. The primary outcome indicator of the study was cognitive function.ResultsThis study included 12 RCTs with 540 participants to evaluate the impact of virtual reality exercise on cognitive function in brain-injured patients. The analysis revealed significant cognitive improvement with an SMD of 0.88 (95% CI: 0.59, 1.17), p = 0.019, and I2 = 51.9% using a random effects model. Sensitivity analysis confirmed robust findings with no significant single study effects. Symmetric funnel plots indicated no publication bias. These results support virtual reality as an effective cognitive intervention for brain-injured patients.ConclusionVirtual reality (VR) sports games significantly enhanced cognitive function, coordination, and reaction speed in brain-injured patients, thereby boosting their learning motivation and engagement.Systematic Review Registrationhttps://www.crd.york.ac.uk/PROSPERO/, identifier CRD42024581533.https://www.frontiersin.org/articles/10.3389/fneur.2025.1579909/fullvirtual game technologybrain-injured patientscognitive functionRCTnovel rehabilitation modality
spellingShingle Yuze Zhang
Yuze Zhang
Haojie Li
Hong Xiao
The study of the effect of virtual reality technology combined with sports games on improving cognitive function in patients with brain injury: a meta analysis of randomized controlled trials
Frontiers in Neurology
virtual game technology
brain-injured patients
cognitive function
RCT
novel rehabilitation modality
title The study of the effect of virtual reality technology combined with sports games on improving cognitive function in patients with brain injury: a meta analysis of randomized controlled trials
title_full The study of the effect of virtual reality technology combined with sports games on improving cognitive function in patients with brain injury: a meta analysis of randomized controlled trials
title_fullStr The study of the effect of virtual reality technology combined with sports games on improving cognitive function in patients with brain injury: a meta analysis of randomized controlled trials
title_full_unstemmed The study of the effect of virtual reality technology combined with sports games on improving cognitive function in patients with brain injury: a meta analysis of randomized controlled trials
title_short The study of the effect of virtual reality technology combined with sports games on improving cognitive function in patients with brain injury: a meta analysis of randomized controlled trials
title_sort study of the effect of virtual reality technology combined with sports games on improving cognitive function in patients with brain injury a meta analysis of randomized controlled trials
topic virtual game technology
brain-injured patients
cognitive function
RCT
novel rehabilitation modality
url https://www.frontiersin.org/articles/10.3389/fneur.2025.1579909/full
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