Metabolic syndrome in obese Turkish children and adolescents: comparison of two diagnostic models

There is no consensus on whether or not the diagnostic criteria of metabolic syndrome (MS) defined for adults [National Cholesterol Education Panel (NCEP) and World Health Organization (WHO)] can be used in childhood as well. We aimed to compare prevalence of metabolic syndrome among obese ch...

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Main Authors: Filiz M Cizmecioğlu, Sükrü Hatun, Sibel Kalaça
Format: Article
Language:English
Published: Hacettepe University Institute of Child Health 2008-08-01
Series:The Turkish Journal of Pediatrics
Online Access:https://turkjpediatr.org/article/view/2447
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author Filiz M Cizmecioğlu
Sükrü Hatun
Sibel Kalaça
author_facet Filiz M Cizmecioğlu
Sükrü Hatun
Sibel Kalaça
author_sort Filiz M Cizmecioğlu
collection DOAJ
description There is no consensus on whether or not the diagnostic criteria of metabolic syndrome (MS) defined for adults [National Cholesterol Education Panel (NCEP) and World Health Organization (WHO)] can be used in childhood as well. We aimed to compare prevalence of metabolic syndrome among obese children and adolescents using WHO and NCEP guidelines. A total of 112 obese children and adolescents were assessed. MS was diagnosed according to both modified WHO and NCEP criteria using cut-off values for children. Abnormal glucose homeostasis was identified in 46.6% of the subjects. Fasting glucose levels for all subjects were less than 110 mg/dl and no subjects had type 2 diabetes. Overall, dyslipidemia was present in 42.9% and hypertension in 42.9% of the subjects. While 24% of the subjects were diagnosed as MS according to NCEP, a rate of 38.8% were diagnosed according to WHO-defined MS. There was a moderate agreement between NCEP and WHO guidelines. More children were diagnosed as MS based on the WHO guidelines. This may lead to better monitoring for these children and prevention of their chronic diseases in the future. Therefore, we recommend using WHO guidelines in the diagnosis of MS with a specific emphasis on definition of abnormal glucose homeostasis.
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spelling doaj-art-44ae8512cb8e4ce4b3e6bf08ad98201f2025-08-20T03:01:15ZengHacettepe University Institute of Child HealthThe Turkish Journal of Pediatrics0041-43012791-64212008-08-01504Metabolic syndrome in obese Turkish children and adolescents: comparison of two diagnostic modelsFiliz M Cizmecioğlu0Sükrü HatunSibel KalaçaDivision of Endocrinology, Department of Pediatrics, Kocaeli University Faculty of Medicine, Kocaeli, Turkey. There is no consensus on whether or not the diagnostic criteria of metabolic syndrome (MS) defined for adults [National Cholesterol Education Panel (NCEP) and World Health Organization (WHO)] can be used in childhood as well. We aimed to compare prevalence of metabolic syndrome among obese children and adolescents using WHO and NCEP guidelines. A total of 112 obese children and adolescents were assessed. MS was diagnosed according to both modified WHO and NCEP criteria using cut-off values for children. Abnormal glucose homeostasis was identified in 46.6% of the subjects. Fasting glucose levels for all subjects were less than 110 mg/dl and no subjects had type 2 diabetes. Overall, dyslipidemia was present in 42.9% and hypertension in 42.9% of the subjects. While 24% of the subjects were diagnosed as MS according to NCEP, a rate of 38.8% were diagnosed according to WHO-defined MS. There was a moderate agreement between NCEP and WHO guidelines. More children were diagnosed as MS based on the WHO guidelines. This may lead to better monitoring for these children and prevention of their chronic diseases in the future. Therefore, we recommend using WHO guidelines in the diagnosis of MS with a specific emphasis on definition of abnormal glucose homeostasis. https://turkjpediatr.org/article/view/2447
spellingShingle Filiz M Cizmecioğlu
Sükrü Hatun
Sibel Kalaça
Metabolic syndrome in obese Turkish children and adolescents: comparison of two diagnostic models
The Turkish Journal of Pediatrics
title Metabolic syndrome in obese Turkish children and adolescents: comparison of two diagnostic models
title_full Metabolic syndrome in obese Turkish children and adolescents: comparison of two diagnostic models
title_fullStr Metabolic syndrome in obese Turkish children and adolescents: comparison of two diagnostic models
title_full_unstemmed Metabolic syndrome in obese Turkish children and adolescents: comparison of two diagnostic models
title_short Metabolic syndrome in obese Turkish children and adolescents: comparison of two diagnostic models
title_sort metabolic syndrome in obese turkish children and adolescents comparison of two diagnostic models
url https://turkjpediatr.org/article/view/2447
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AT sukruhatun metabolicsyndromeinobeseturkishchildrenandadolescentscomparisonoftwodiagnosticmodels
AT sibelkalaca metabolicsyndromeinobeseturkishchildrenandadolescentscomparisonoftwodiagnosticmodels