The Cholinergic Amelioration of Sepsis-Induced Baroreflex Dysfunction and Brainstem Inflammation Is Negated by Central Adenosine A3 Receptors

The Cholinergic Amelioration of Sepsis-Induced Baroreflex Dysfunction and Brainstem Inflammation Is Negated by Central Adenosine A3 Receptors

<b>Background/Objectives</b>: Sepsis has been shown to depress arterial baroreceptor function, and this effect is counterbalanced by the cholinergic anti-inflammatory pathway. Considering the importance of central adenosine receptors in baroreceptor function, this study tested whether ce...

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Bibliographic Details
Main Authors: Amany E. El-Naggar, Mai M. Helmy, Sahar M. El-Gowilly, Mahmoud M. El-Mas
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Pharmaceuticals
Subjects:
sepsis
reflex bradycardia
nicotine
adenosine A3 receptors
neuroinflammation
nucleus tractus solitarius
Online Access:https://www.mdpi.com/1424-8247/18/3/388
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