Erythema Multiforme Attributable to Herpes Simplex Virus: Clinical Aspects and Treatment

Erythema multiforme is an acute mucocutaneous hypersensitivity reaction with various etiological factors, including herpes simplex virus, medications, autoimmune diseases, and malignancies, but the most common cause is infection by herpes simplex virus. The most characteristic feature is the presenc...

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Main Authors: Aya Mtiri, Ghada Bouslama, Nour-sayda Ben Messouad, Iyadh Abidi, Souha Ben Youssef, Badreddine Sriha
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Case Reports in Dentistry
Online Access:http://dx.doi.org/10.1155/2021/6692495
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author Aya Mtiri
Ghada Bouslama
Nour-sayda Ben Messouad
Iyadh Abidi
Souha Ben Youssef
Badreddine Sriha
author_facet Aya Mtiri
Ghada Bouslama
Nour-sayda Ben Messouad
Iyadh Abidi
Souha Ben Youssef
Badreddine Sriha
author_sort Aya Mtiri
collection DOAJ
description Erythema multiforme is an acute mucocutaneous hypersensitivity reaction with various etiological factors, including herpes simplex virus, medications, autoimmune diseases, and malignancies, but the most common cause is infection by herpes simplex virus. The most characteristic feature is the presence of “target lesions.” There are no specific diagnostic tests for EM, and the diagnosis is based on clinical signs and symptoms and biopsy if required. We report a case of recurrent herpes-associated erythema multiforme managed with prophylactic acyclovir for 6 months: a 17-year-old boy had recurrent cutaneous lesions as well as lesions in the oral cavity and lips. Positive serology for herpes simplex virus and histopathological examination confirmed the diagnosis.
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institution Kabale University
issn 2090-6447
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language English
publishDate 2021-01-01
publisher Wiley
record_format Article
series Case Reports in Dentistry
spelling doaj-art-44973b6e8f3e471ca32f990ca902159e2025-02-03T00:58:47ZengWileyCase Reports in Dentistry2090-64472090-64552021-01-01202110.1155/2021/66924956692495Erythema Multiforme Attributable to Herpes Simplex Virus: Clinical Aspects and TreatmentAya Mtiri0Ghada Bouslama1Nour-sayda Ben Messouad2Iyadh Abidi3Souha Ben Youssef4Badreddine Sriha5Department of Oral Surgery, University Hospital Farhat Hached Sousse, University of Monastir, TunisiaDepartment of Oral Surgery, University Hospital Farhat Hached Sousse, University of Monastir, TunisiaDepartment of Oral Surgery, University Hospital Farhat Hached Sousse, University of Monastir, TunisiaDepartment of Oral Surgery, University Hospital Farhat Hached Sousse, University of Monastir, TunisiaDepartment of Oral Surgery, University Hospital Farhat Hached Sousse, University of Monastir, TunisiaDepartment of Histopathology, University Hospital Farhat Hached, Sousse, TunisiaErythema multiforme is an acute mucocutaneous hypersensitivity reaction with various etiological factors, including herpes simplex virus, medications, autoimmune diseases, and malignancies, but the most common cause is infection by herpes simplex virus. The most characteristic feature is the presence of “target lesions.” There are no specific diagnostic tests for EM, and the diagnosis is based on clinical signs and symptoms and biopsy if required. We report a case of recurrent herpes-associated erythema multiforme managed with prophylactic acyclovir for 6 months: a 17-year-old boy had recurrent cutaneous lesions as well as lesions in the oral cavity and lips. Positive serology for herpes simplex virus and histopathological examination confirmed the diagnosis.http://dx.doi.org/10.1155/2021/6692495
spellingShingle Aya Mtiri
Ghada Bouslama
Nour-sayda Ben Messouad
Iyadh Abidi
Souha Ben Youssef
Badreddine Sriha
Erythema Multiforme Attributable to Herpes Simplex Virus: Clinical Aspects and Treatment
Case Reports in Dentistry
title Erythema Multiforme Attributable to Herpes Simplex Virus: Clinical Aspects and Treatment
title_full Erythema Multiforme Attributable to Herpes Simplex Virus: Clinical Aspects and Treatment
title_fullStr Erythema Multiforme Attributable to Herpes Simplex Virus: Clinical Aspects and Treatment
title_full_unstemmed Erythema Multiforme Attributable to Herpes Simplex Virus: Clinical Aspects and Treatment
title_short Erythema Multiforme Attributable to Herpes Simplex Virus: Clinical Aspects and Treatment
title_sort erythema multiforme attributable to herpes simplex virus clinical aspects and treatment
url http://dx.doi.org/10.1155/2021/6692495
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