Current Status and Future Perspectives of Immunotherapies in Bladder Cancer
Bladder cancer exhibits a broad spectrum of progression, ranging from early stage to metastatic disease. Approximately 75% of newly diagnosed patients present with non-muscle-invasive bladder cancer, while the remaining 25% have muscle-invasive bladder cancer or metastatic disease. The prognosis of...
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| Format: | Article |
| Language: | English |
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Galenos Publishing House
2025-08-01
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| Series: | Acta Haematologica Oncologica Turcica |
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| Online Access: | https://www.actaoncologicaturcica.com/articles/current-status-and-future-perspectives-of-immunotherapies-in-bladder-cancer/doi/ahot.galenos.2025.2025-3-2 |
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| _version_ | 1849340528952344576 |
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| author | Gökhan Çolak Bilgin Demir |
| author_facet | Gökhan Çolak Bilgin Demir |
| author_sort | Gökhan Çolak |
| collection | DOAJ |
| description | Bladder cancer exhibits a broad spectrum of progression, ranging from early stage to metastatic disease. Approximately 75% of newly diagnosed patients present with non-muscle-invasive bladder cancer, while the remaining 25% have muscle-invasive bladder cancer or metastatic disease. The prognosis of advanced urothelial carcinoma is poor, with more than 90% of patients succumbing to metastatic disease within five years of diagnosis. In recent years, the role of immunotherapies, particularly immune checkpoint inhibitors, in the treatment of bladder cancer has become increasingly recognized. This review aims to evaluate the current status of immunotherapies in bladder cancer and their future potential. |
| format | Article |
| id | doaj-art-448fab282a1d46d0aefa3df1f998bd26 |
| institution | Kabale University |
| issn | 3061-9947 |
| language | English |
| publishDate | 2025-08-01 |
| publisher | Galenos Publishing House |
| record_format | Article |
| series | Acta Haematologica Oncologica Turcica |
| spelling | doaj-art-448fab282a1d46d0aefa3df1f998bd262025-08-20T03:43:54ZengGalenos Publishing HouseActa Haematologica Oncologica Turcica3061-99472025-08-01582617310.4274/ahot.galenos.2025.2025-3-2Current Status and Future Perspectives of Immunotherapies in Bladder CancerGökhan Çolak0https://orcid.org/0000-0002-3802-461XBilgin Demir1https://orcid.org/0000-0003-4380-9419Aydın Adnan Menderes University Faculty of Medicine Department of Medical Oncology, Aydın, TürkiyeAydın Adnan Menderes University Faculty of Medicine Department of Medical Oncology, Aydın, TürkiyeBladder cancer exhibits a broad spectrum of progression, ranging from early stage to metastatic disease. Approximately 75% of newly diagnosed patients present with non-muscle-invasive bladder cancer, while the remaining 25% have muscle-invasive bladder cancer or metastatic disease. The prognosis of advanced urothelial carcinoma is poor, with more than 90% of patients succumbing to metastatic disease within five years of diagnosis. In recent years, the role of immunotherapies, particularly immune checkpoint inhibitors, in the treatment of bladder cancer has become increasingly recognized. This review aims to evaluate the current status of immunotherapies in bladder cancer and their future potential.https://www.actaoncologicaturcica.com/articles/current-status-and-future-perspectives-of-immunotherapies-in-bladder-cancer/doi/ahot.galenos.2025.2025-3-2bladder cancercheckpoint inhibitorsimmunotherapy |
| spellingShingle | Gökhan Çolak Bilgin Demir Current Status and Future Perspectives of Immunotherapies in Bladder Cancer Acta Haematologica Oncologica Turcica bladder cancer checkpoint inhibitors immunotherapy |
| title | Current Status and Future Perspectives of Immunotherapies in Bladder Cancer |
| title_full | Current Status and Future Perspectives of Immunotherapies in Bladder Cancer |
| title_fullStr | Current Status and Future Perspectives of Immunotherapies in Bladder Cancer |
| title_full_unstemmed | Current Status and Future Perspectives of Immunotherapies in Bladder Cancer |
| title_short | Current Status and Future Perspectives of Immunotherapies in Bladder Cancer |
| title_sort | current status and future perspectives of immunotherapies in bladder cancer |
| topic | bladder cancer checkpoint inhibitors immunotherapy |
| url | https://www.actaoncologicaturcica.com/articles/current-status-and-future-perspectives-of-immunotherapies-in-bladder-cancer/doi/ahot.galenos.2025.2025-3-2 |
| work_keys_str_mv | AT gokhancolak currentstatusandfutureperspectivesofimmunotherapiesinbladdercancer AT bilgindemir currentstatusandfutureperspectivesofimmunotherapiesinbladdercancer |