HOLTER ECG MONITORING AND TREATMENT EFFECTIVENESS CONTROL IN PATIENTS AFTER MYOCARDIAL INFARCTION

In total, 316 patients after Q wave myocardial infarction (Q-MI) were randomised into 3 groups. For 6 months after discharge, the control group (n=103) received standard therapy (aspirin, enalapril, metoprolol, simvastatin). Group 1 (n=107) also received trimetazidine, and Group 2 (n=106) was admini...

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Main Authors: U. A. Islamova, R. M. Gafurova, A. A. Abdullaev, I. A. Kadieva, Kh. M. Mutalipov
Format: Article
Language:Russian
Published: «FIRMA «SILICEA» LLC 2010-12-01
Series:Российский кардиологический журнал
Subjects:
Online Access:https://russjcardiol.elpub.ru/jour/article/view/1510
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author U. A. Islamova
R. M. Gafurova
A. A. Abdullaev
I. A. Kadieva
Kh. M. Mutalipov
author_facet U. A. Islamova
R. M. Gafurova
A. A. Abdullaev
I. A. Kadieva
Kh. M. Mutalipov
author_sort U. A. Islamova
collection DOAJ
description In total, 316 patients after Q wave myocardial infarction (Q-MI) were randomised into 3 groups. For 6 months after discharge, the control group (n=103) received standard therapy (aspirin, enalapril, metoprolol, simvastatin). Group 1 (n=107) also received trimetazidine, and Group 2 (n=106) was administered ramipril, carvedilol, and trimetazidine. At baseline, 6 months and 2 years later, 24-hour Holter ECG monitoring was performed. The combination of ramipril, carvedilol, and trimetazidine (Group 2) was the most effective in prevention of pain and painless episodes of myocardial ischemia, as well as in reduction of supraventricular and ventricular extrasystolia incidence. The combination of enalapril, metoprolol, and trimetazidine (Group 1) was less effective than Group 2 treatment, but more effective than the therapy in the control group (enalapril, metoprolol, and standard therapy, without trimetazidine treatment).
format Article
id doaj-art-4480dbfe53464543be53c73e1bd3e021
institution Kabale University
issn 1560-4071
2618-7620
language Russian
publishDate 2010-12-01
publisher «FIRMA «SILICEA» LLC
record_format Article
series Российский кардиологический журнал
spelling doaj-art-4480dbfe53464543be53c73e1bd3e0212025-08-20T03:35:11Zrus«FIRMA «SILICEA» LLCРоссийский кардиологический журнал1560-40712618-76202010-12-010623271297HOLTER ECG MONITORING AND TREATMENT EFFECTIVENESS CONTROL IN PATIENTS AFTER MYOCARDIAL INFARCTIONU. A. Islamova0R. M. Gafurova1A. A. Abdullaev2I. A. Kadieva3Kh. M. Mutalipov4Дагестанская государственная медицинская академия Росздрава, кафедра поликлинической терапии, кардиологии и общей врачебной практики, МахачкалаДагестанская государственная медицинская академия Росздрава, кафедра поликлинической терапии, кардиологии и общей врачебной практики, МахачкалаДагестанская государственная медицинская академия Росздрава, кафедра поликлинической терапии, кардиологии и общей врачебной практики, МахачкалаДагестанская государственная медицинская академия Росздрава, кафедра поликлинической терапии, кардиологии и общей врачебной практики, МахачкалаДагестанская государственная медицинская академия Росздрава, кафедра поликлинической терапии, кардиологии и общей врачебной практики, МахачкалаIn total, 316 patients after Q wave myocardial infarction (Q-MI) were randomised into 3 groups. For 6 months after discharge, the control group (n=103) received standard therapy (aspirin, enalapril, metoprolol, simvastatin). Group 1 (n=107) also received trimetazidine, and Group 2 (n=106) was administered ramipril, carvedilol, and trimetazidine. At baseline, 6 months and 2 years later, 24-hour Holter ECG monitoring was performed. The combination of ramipril, carvedilol, and trimetazidine (Group 2) was the most effective in prevention of pain and painless episodes of myocardial ischemia, as well as in reduction of supraventricular and ventricular extrasystolia incidence. The combination of enalapril, metoprolol, and trimetazidine (Group 1) was less effective than Group 2 treatment, but more effective than the therapy in the control group (enalapril, metoprolol, and standard therapy, without trimetazidine treatment).https://russjcardiol.elpub.ru/jour/article/view/1510post-infarction period24-hour ecg monitoringramiprilcarvediloltrimetazidineenalaprilmetoprolol
spellingShingle U. A. Islamova
R. M. Gafurova
A. A. Abdullaev
I. A. Kadieva
Kh. M. Mutalipov
HOLTER ECG MONITORING AND TREATMENT EFFECTIVENESS CONTROL IN PATIENTS AFTER MYOCARDIAL INFARCTION
Российский кардиологический журнал
post-infarction period
24-hour ecg monitoring
ramipril
carvedilol
trimetazidine
enalapril
metoprolol
title HOLTER ECG MONITORING AND TREATMENT EFFECTIVENESS CONTROL IN PATIENTS AFTER MYOCARDIAL INFARCTION
title_full HOLTER ECG MONITORING AND TREATMENT EFFECTIVENESS CONTROL IN PATIENTS AFTER MYOCARDIAL INFARCTION
title_fullStr HOLTER ECG MONITORING AND TREATMENT EFFECTIVENESS CONTROL IN PATIENTS AFTER MYOCARDIAL INFARCTION
title_full_unstemmed HOLTER ECG MONITORING AND TREATMENT EFFECTIVENESS CONTROL IN PATIENTS AFTER MYOCARDIAL INFARCTION
title_short HOLTER ECG MONITORING AND TREATMENT EFFECTIVENESS CONTROL IN PATIENTS AFTER MYOCARDIAL INFARCTION
title_sort holter ecg monitoring and treatment effectiveness control in patients after myocardial infarction
topic post-infarction period
24-hour ecg monitoring
ramipril
carvedilol
trimetazidine
enalapril
metoprolol
url https://russjcardiol.elpub.ru/jour/article/view/1510
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AT aaabdullaev holterecgmonitoringandtreatmenteffectivenesscontrolinpatientsaftermyocardialinfarction
AT iakadieva holterecgmonitoringandtreatmenteffectivenesscontrolinpatientsaftermyocardialinfarction
AT khmmutalipov holterecgmonitoringandtreatmenteffectivenesscontrolinpatientsaftermyocardialinfarction