Effectiveness of Platelet-Rich Plasma in Treating Rotator Cuff Tendinopathy: A Systematic Review and Meta-Analysis
Introduction: Rotator cuff tendinopathy often causes significant shoulder pain and limits function. Traditional treatments, such as physical therapy and corticosteroid injections, provide inconsistent relief. Platelet-rich plasma (PRP) has emerged as a promising regenerative therapy for pain relief...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Indian Orthopaedic Research Group
2025-03-01
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| Series: | Journal of Orthopaedic Case Reports |
| Subjects: | |
| Online Access: | https://jocr.co.in/wp/2025/03/01/effectiveness-of-platelet-rich-plasma-in-treating-rotator-cuff-tendinopathy-a-systematic-review-and-meta-analysis/ |
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| Summary: | Introduction:
Rotator cuff tendinopathy often causes significant shoulder pain and limits function. Traditional treatments, such as physical therapy and corticosteroid injections, provide inconsistent relief. Platelet-rich plasma (PRP) has emerged as a promising regenerative therapy for pain relief and tendon healing. This systematic review and meta-analysis evaluated PRP’s effectiveness compared to placebo or other treatments.
Materials and Methods:
A thorough search of PubMed, Embase, and Cochrane Library focused on randomized controlled trials (RCTs) using PRP as a primary intervention for rotator cuff tendinopathy. Eligible studies included pain reduction, functional improvement, and retear rates as outcomes. Data were extracted and analyzed using standardized methods.
Results:
Thirty RCTs with around 2,500 participants were included in the study. PRP significantly reduced pain and improved function in the short term compared to placebo and corticosteroids. However, long-term benefits (beyond 12 months) were limited, with retear rates and function similar to control groups.
Conclusion:
PRP provides significant short-term pain relief and functional improvement in rotator cuff tendinopathy but does not demonstrate superior long-term benefits over placebo or corticosteroids. |
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| ISSN: | 2250-0685 2321-3817 |