The incidence and risk factors of neural tube defects in Izmir, Turkey: a nested case-control study

The aim of this study was to determine the incidence of neural tube defects (NTDs) in Izmir, Turkey, and to evaluate risk factors that may be associated with NTD-affected pregnancies. A nested case-control study was carried out in all hospitals in Izmir. Controls were matched with cases on an...

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Main Authors: Aliye Mandiracioğlu, Ibrahim Ulman, Emel Lüleci, Cevval Ulman
Format: Article
Language:English
Published: Hacettepe University Institute of Child Health 2004-07-01
Series:The Turkish Journal of Pediatrics
Online Access:https://turkjpediatr.org/article/view/2805
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author Aliye Mandiracioğlu
Ibrahim Ulman
Emel Lüleci
Cevval Ulman
author_facet Aliye Mandiracioğlu
Ibrahim Ulman
Emel Lüleci
Cevval Ulman
author_sort Aliye Mandiracioğlu
collection DOAJ
description The aim of this study was to determine the incidence of neural tube defects (NTDs) in Izmir, Turkey, and to evaluate risk factors that may be associated with NTD-affected pregnancies. A nested case-control study was carried out in all hospitals in Izmir. Controls were matched with cases on an individual basis according to the newborn's age and hospital in which they were born. There were 56 newborns with NTD out of 36,331 deliveries in Izmir hospitals in 2000. The incidence of NTD was 1.5 per 1000 births. Forty-four cases and 88 controls were analyzed for risk factors. According to chi-square analysis, maternal education, paternal education, maternal nutritional status, maternal drug usage, and presence of maternal chronic diseases and acute infections during pregnancy were found significantly different between case and control groups.
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institution OA Journals
issn 0041-4301
2791-6421
language English
publishDate 2004-07-01
publisher Hacettepe University Institute of Child Health
record_format Article
series The Turkish Journal of Pediatrics
spelling doaj-art-4463da5bb3b6456399013b68b693d5df2025-08-20T02:01:57ZengHacettepe University Institute of Child HealthThe Turkish Journal of Pediatrics0041-43012791-64212004-07-01463The incidence and risk factors of neural tube defects in Izmir, Turkey: a nested case-control studyAliye Mandiracioğlu0Ibrahim UlmanEmel LüleciCevval UlmanDepartment of Public Health, Ege University Faculty of Medicine, Izmir, Turkey. The aim of this study was to determine the incidence of neural tube defects (NTDs) in Izmir, Turkey, and to evaluate risk factors that may be associated with NTD-affected pregnancies. A nested case-control study was carried out in all hospitals in Izmir. Controls were matched with cases on an individual basis according to the newborn's age and hospital in which they were born. There were 56 newborns with NTD out of 36,331 deliveries in Izmir hospitals in 2000. The incidence of NTD was 1.5 per 1000 births. Forty-four cases and 88 controls were analyzed for risk factors. According to chi-square analysis, maternal education, paternal education, maternal nutritional status, maternal drug usage, and presence of maternal chronic diseases and acute infections during pregnancy were found significantly different between case and control groups. https://turkjpediatr.org/article/view/2805
spellingShingle Aliye Mandiracioğlu
Ibrahim Ulman
Emel Lüleci
Cevval Ulman
The incidence and risk factors of neural tube defects in Izmir, Turkey: a nested case-control study
The Turkish Journal of Pediatrics
title The incidence and risk factors of neural tube defects in Izmir, Turkey: a nested case-control study
title_full The incidence and risk factors of neural tube defects in Izmir, Turkey: a nested case-control study
title_fullStr The incidence and risk factors of neural tube defects in Izmir, Turkey: a nested case-control study
title_full_unstemmed The incidence and risk factors of neural tube defects in Izmir, Turkey: a nested case-control study
title_short The incidence and risk factors of neural tube defects in Izmir, Turkey: a nested case-control study
title_sort incidence and risk factors of neural tube defects in izmir turkey a nested case control study
url https://turkjpediatr.org/article/view/2805
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