Gut microbiota regulates serum metabolites in mice with nonalcoholic fatty liver disease via gut metabolites: mechanisms involving branched-chain amino acids and unsaturated fatty acids

Gut microbiota regulates serum metabolites in mice with nonalcoholic fatty liver disease via gut metabolites: mechanisms involving branched-chain amino acids and unsaturated fatty acids

IntroductionIn recent years, nonalcoholic fatty liver disease (NAFLD) has become the most common chronic liver disease globally. Studies indicate that the gut-liver axis plays an important role in the occurrence and development of this disease. Our previous studies showed that the gut microbiota and...

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Main Authors: Hao Qiu, Yuhang Wen, Yadan Luo, Shuya Lv, Jingrong Huang, Baoting Chen, Ruilin Lu, Lvqin He, Qian Yang, Jianhong Han, Xuefeng Yan, Manli He, Mingde Zhao, Xiaoxia Zou, Congwei Gu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Endocrinology
Subjects:
nonalcoholic fatty liver disease
serum metabolites
gut microbiota
gut metabolites
metabonomics
MetOrigin
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2025.1606669/full
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