Purity determination of glutamic acid by DSC

Objective: The feasibility of the determination of glutamate purity was studied by differential scanning calorimetry. Methods: Indium and Zinc were used to correct the instrument parameters. Under the conditions of nitrogen atmosphere and flow rate of 50 mL/min, the effects of sample particle size,...

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Main Authors: MA Ying-nan, LI Yu-pu, LIU Bei-lei, MA Yu-song, YAO Chun-yi, HOU Lan-jing
Format: Article
Language:English
Published: The Editorial Office of Food and Machinery 2023-06-01
Series:Shipin yu jixie
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Online Access:http://www.ifoodmm.com/spyjxen/article/abstract/20230409
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author MA Ying-nan
LI Yu-pu
LIU Bei-lei
MA Yu-song
YAO Chun-yi
HOU Lan-jing
author_facet MA Ying-nan
LI Yu-pu
LIU Bei-lei
MA Yu-song
YAO Chun-yi
HOU Lan-jing
author_sort MA Ying-nan
collection DOAJ
description Objective: The feasibility of the determination of glutamate purity was studied by differential scanning calorimetry. Methods: Indium and Zinc were used to correct the instrument parameters. Under the conditions of nitrogen atmosphere and flow rate of 50 mL/min, the effects of sample particle size, experimental atmosphere, heating rate and sample quality on the DSC measurement results were investigated, and the glutamic acid purity was determined under the optimal conditions. The determination results were compared between DSC and China Pharmacopeia 2015 titration. Results: Under the condition of weighing 3 mg and heating rate at 40 ℃/min, the purity of glutamic acid was 99.74% and the precision was 0.07%. The purity of glutamic acid measured by titration 99.72%. Conclusion: The DSC method has high accuracy and simple operation, and can be used for the determination of glutamate purity.
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institution OA Journals
issn 1003-5788
language English
publishDate 2023-06-01
publisher The Editorial Office of Food and Machinery
record_format Article
series Shipin yu jixie
spelling doaj-art-445c607f982e470eabb3b0d1f98b970b2025-08-20T02:21:49ZengThe Editorial Office of Food and MachineryShipin yu jixie1003-57882023-06-013945154,10210.13652/j.spjx.1003.5788.2022.80414Purity determination of glutamic acid by DSCMA Ying-nan0LI Yu-pu1LIU Bei-lei2MA Yu-song3YAO Chun-yi4HOU Lan-jing5 Technical Center of Shijiazhuang Customs District, Shijiazhuang, Hebei 050051 , China Technical Center of Shijiazhuang Customs District, Shijiazhuang, Hebei 050051 , China Technical Center of Shijiazhuang Customs District, Shijiazhuang, Hebei 050051 , China Technical Center of Shijiazhuang Customs District, Shijiazhuang, Hebei 050051 , China Technical Center of Shijiazhuang Customs District, Shijiazhuang, Hebei 050051 , China Technical Center of Shijiazhuang Customs District, Shijiazhuang, Hebei 050051 , China Objective: The feasibility of the determination of glutamate purity was studied by differential scanning calorimetry. Methods: Indium and Zinc were used to correct the instrument parameters. Under the conditions of nitrogen atmosphere and flow rate of 50 mL/min, the effects of sample particle size, experimental atmosphere, heating rate and sample quality on the DSC measurement results were investigated, and the glutamic acid purity was determined under the optimal conditions. The determination results were compared between DSC and China Pharmacopeia 2015 titration. Results: Under the condition of weighing 3 mg and heating rate at 40 ℃/min, the purity of glutamic acid was 99.74% and the precision was 0.07%. The purity of glutamic acid measured by titration 99.72%. Conclusion: The DSC method has high accuracy and simple operation, and can be used for the determination of glutamate purity.http://www.ifoodmm.com/spyjxen/article/abstract/20230409 differential scanning calorimetry glutamic acid purity
spellingShingle MA Ying-nan
LI Yu-pu
LIU Bei-lei
MA Yu-song
YAO Chun-yi
HOU Lan-jing
Purity determination of glutamic acid by DSC
Shipin yu jixie
differential scanning calorimetry
glutamic acid
purity
title Purity determination of glutamic acid by DSC
title_full Purity determination of glutamic acid by DSC
title_fullStr Purity determination of glutamic acid by DSC
title_full_unstemmed Purity determination of glutamic acid by DSC
title_short Purity determination of glutamic acid by DSC
title_sort purity determination of glutamic acid by dsc
topic differential scanning calorimetry
glutamic acid
purity
url http://www.ifoodmm.com/spyjxen/article/abstract/20230409
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