Angioedema Secondary to IV Tissue Plasminogen Activator Administration for Treatment of Acute Ischemic Stroke
Background. IV tissue plasminogen activator (tPA) is the treatment of choice for ischemic strokes that present within the treatment window. In the majority of patients, this offers an effective and often life-prolonging treatment in the acute setting. In a rare set of patients treated with IV tPA, s...
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | Case Reports in Critical Care |
| Online Access: | http://dx.doi.org/10.1155/2018/3257215 |
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| _version_ | 1832556950182690816 |
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| author | Benjamin Chaucer Dustin Whelan Christopher Veys Manas Upadhyaya |
| author_facet | Benjamin Chaucer Dustin Whelan Christopher Veys Manas Upadhyaya |
| author_sort | Benjamin Chaucer |
| collection | DOAJ |
| description | Background. IV tissue plasminogen activator (tPA) is the treatment of choice for ischemic strokes that present within the treatment window. In the majority of patients, this offers an effective and often life-prolonging treatment in the acute setting. In a rare set of patients treated with IV tPA, side effects can be seen. One rare and potentially dangerous side effect is angioedema. Case Report. We present the case of a patient treated for ischemic stroke who developed angioedema and discuss the etiology and risk factors for this rare, but dangerous side effect. Conclusion. Given the frequent and widespread use of tPA, awareness of the rare life-threatening side effects is paramount. This is of particular importance for practitioners in the acute care setting. |
| format | Article |
| id | doaj-art-444d85ab4b754f5bbdf7dab0a73519c3 |
| institution | Kabale University |
| issn | 2090-6420 2090-6439 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Critical Care |
| spelling | doaj-art-444d85ab4b754f5bbdf7dab0a73519c32025-02-03T05:43:58ZengWileyCase Reports in Critical Care2090-64202090-64392018-01-01201810.1155/2018/32572153257215Angioedema Secondary to IV Tissue Plasminogen Activator Administration for Treatment of Acute Ischemic StrokeBenjamin Chaucer0Dustin Whelan1Christopher Veys2Manas Upadhyaya3University of Illinois College of Medicine at Peoria, 1 Illini Dr, Peoria, IL 61605, USAUniversity of Illinois College of Medicine at Peoria, 1 Illini Dr, Peoria, IL 61605, USAUniversity of Illinois College of Medicine at Peoria, 1 Illini Dr, Peoria, IL 61605, USAIllinois Neurological Institute, OSF Saint Francis Medical Center, Peoria, IL, USABackground. IV tissue plasminogen activator (tPA) is the treatment of choice for ischemic strokes that present within the treatment window. In the majority of patients, this offers an effective and often life-prolonging treatment in the acute setting. In a rare set of patients treated with IV tPA, side effects can be seen. One rare and potentially dangerous side effect is angioedema. Case Report. We present the case of a patient treated for ischemic stroke who developed angioedema and discuss the etiology and risk factors for this rare, but dangerous side effect. Conclusion. Given the frequent and widespread use of tPA, awareness of the rare life-threatening side effects is paramount. This is of particular importance for practitioners in the acute care setting.http://dx.doi.org/10.1155/2018/3257215 |
| spellingShingle | Benjamin Chaucer Dustin Whelan Christopher Veys Manas Upadhyaya Angioedema Secondary to IV Tissue Plasminogen Activator Administration for Treatment of Acute Ischemic Stroke Case Reports in Critical Care |
| title | Angioedema Secondary to IV Tissue Plasminogen Activator Administration for Treatment of Acute Ischemic Stroke |
| title_full | Angioedema Secondary to IV Tissue Plasminogen Activator Administration for Treatment of Acute Ischemic Stroke |
| title_fullStr | Angioedema Secondary to IV Tissue Plasminogen Activator Administration for Treatment of Acute Ischemic Stroke |
| title_full_unstemmed | Angioedema Secondary to IV Tissue Plasminogen Activator Administration for Treatment of Acute Ischemic Stroke |
| title_short | Angioedema Secondary to IV Tissue Plasminogen Activator Administration for Treatment of Acute Ischemic Stroke |
| title_sort | angioedema secondary to iv tissue plasminogen activator administration for treatment of acute ischemic stroke |
| url | http://dx.doi.org/10.1155/2018/3257215 |
| work_keys_str_mv | AT benjaminchaucer angioedemasecondarytoivtissueplasminogenactivatoradministrationfortreatmentofacuteischemicstroke AT dustinwhelan angioedemasecondarytoivtissueplasminogenactivatoradministrationfortreatmentofacuteischemicstroke AT christopherveys angioedemasecondarytoivtissueplasminogenactivatoradministrationfortreatmentofacuteischemicstroke AT manasupadhyaya angioedemasecondarytoivtissueplasminogenactivatoradministrationfortreatmentofacuteischemicstroke |