Epimedin B protects against bone loss and inflammation in diabetic osteoporosis rats by regulating OPG/RANKL pathway

Epimedin B protects against bone loss and inflammation in diabetic osteoporosis rats by regulating OPG/RANKL pathway

Abstract Background Diabetes is a common disease contributing to osteoporosis. Epimedin B (EB), a major ingredient of Herba Epimedii, has been found to be effective in preventing osteoporosis in mice. However, the potential of EB to ameliorate diabetic osteoporosis (DOP) remains elusive. In this stu...

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Bibliographic Details
Main Authors: Xianmei Zhang, Qinguo Sun, Xie Xie, Meng Luo, Junjie Zan, Zewei Cong
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Diabetes
Osteoporosis
Epimedin B
Bone formation
Bone resorption
Inflammation
Online Access:https://doi.org/10.1186/s13018-025-05685-4
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