No correlation was observed between vitamin D levels and disability of patients with multiple sclerosis between latitudes 18° and 30° South

No correlation was observed between vitamin D levels and disability of patients with multiple sclerosis between latitudes 18° and 30° South

ABSTRACT Objective: Vitamin D has taken center stage in research and treatment of multiple sclerosis (MS). The objective of the present study was to assess the serum vitamin D levels of a large population of patients with MS and controls living in a restricted tropical area. Methods: Data from 535...

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Main Authors: Yara Dadalti Fragoso, Tarso Adoni, Soniza Vieira Alves-Leon, Samira L. Apostolos-Pereira, Walter Oleschko Arruda, Joseph B. Bidin Brooks, Henrique S. Rodrigues Cal, Carlos A. Albuquerque Damasceno, Paulo Diniz Gama, Marcus V. Magno Goncalves, Carlos A. da Silva de Jesus, Suzana C. Nunes Machado, Letícia Fezer Mansur, Andre P. da Cunha Matta, Maria Fernanda Mendes, Rogerio Rizo Morales, Adaucto Wanderley da Nobrega-Jr, Monica K. Fiuza Parolin, Mario Pietro Peres, Marlise de Castro Ribeiro, Heloisa Helena Ruocco, Simone Scherpenhuijzen, Fabio Siquinelli, Patrick N. Stoney, Daniel Lima Varela, Audred Cristina Biondo Eboni, Caroline Vieira Spessotto, Elisa Teixeira da Rocha, Pamela Emanuele Lacerda
Format: Article
Language:English
Published: Thieme Revinter Publicações
Series:Arquivos de Neuro-Psiquiatria
Subjects:
vitamina D
esclerose múltipla
latitude
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2017000100003&lng=en&tlng=en
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Summary:ABSTRACT Objective: Vitamin D has taken center stage in research and treatment of multiple sclerosis (MS). The objective of the present study was to assess the serum vitamin D levels of a large population of patients with MS and controls living in a restricted tropical area. Methods: Data from 535 patients with MS and 350 control subjects were obtained from 14 cities around the Tropic of Capricorn. Results: The mean serum 25-OH vitamin D level was 26.07 ± 10.27 ng/mL for the control subjects, and 28.03 ± 12.19 ng/mL for patients with MS. No correlation was observed between vitamin D levels and the disability of patients over the disease duration. Conclusion: At least for the region around the Tropic of Capricorn, serum levels of vitamin D typically are within the range of 20 to 30 ng/mL for controls and patients with MS.
ISSN:1678-4227

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