Assessment of sleep-disordered breathing in pediatric otitis media with effusion

Background: Given the role of adenoid in the pathogenesis of otitis media with effusion (OME) and sleep-disordered breathing (SDB), the present study aimed to investigate the sleep quality and the impact of adenoidectomy on improvement of sleep symptoms in children with OME. Methods: Children with S...

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Main Authors: Chien-Chia Huang, Pei-Wen Wu, Cheng-Hsun Chiu, Ta-Jen Lee, Chyi-Liang Chen
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Pediatrics and Neonatology
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Online Access:http://www.sciencedirect.com/science/article/pii/S1875957221001352
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author Chien-Chia Huang
Pei-Wen Wu
Cheng-Hsun Chiu
Ta-Jen Lee
Chyi-Liang Chen
author_facet Chien-Chia Huang
Pei-Wen Wu
Cheng-Hsun Chiu
Ta-Jen Lee
Chyi-Liang Chen
author_sort Chien-Chia Huang
collection DOAJ
description Background: Given the role of adenoid in the pathogenesis of otitis media with effusion (OME) and sleep-disordered breathing (SDB), the present study aimed to investigate the sleep quality and the impact of adenoidectomy on improvement of sleep symptoms in children with OME. Methods: Children with SDB or OME, aged 3–12 years, were prospectively enrolled before undergoing adenoidectomy in a tertiary medical center. The symptom severity of obstructive sleep apnea syndrome (OSAS) was evaluated by OSA-18 questionnaire on the day before and 6 months after surgery. Results: In total, 79 pediatric patients including 50 children with SDB and 29 children with OME were enrolled. The mean total OSA-18 score was 56.5 ± 15.1 and ten (34.5%) children experienced moderate to severe symptoms of OSAS as indicated by OSA-18 score ≥ 60 in OME group. After surgery, patients in both SDB and OME groups experienced improvement (both p < 0.001) and presented no difference in the scores of OSA-18. The proportional change in OSA-18 scores after surgery was related to pre-operative OSA-18 scores and BMI in OME patients (rs = 0.400 and 0.542, p = 0.047 and 0.008), and to pre-operative OSA-18 scores in patients with SDB (rs = 0.393, p = 0.008). Conclusion: Children with OME experienced significant symptoms of OSAS and associated impairment of quality of life. Adenoidectomy is effective in the improvement of sleep symptoms in these patients. Comprehensive assessment of sleep breathing as planning surgery for OME children is suggested.
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spelling doaj-art-443370248dd741efac6502e257a33f572025-08-20T02:28:05ZengElsevierPediatrics and Neonatology1875-95722022-01-01631253210.1016/j.pedneo.2021.06.013Assessment of sleep-disordered breathing in pediatric otitis media with effusionChien-Chia Huang0Pei-Wen Wu1Cheng-Hsun Chiu2Ta-Jen Lee3Chyi-Liang Chen4Division of Rhinology, Department of Otolaryngology, Chang Gung Memorial Hospital and Chang Gung University, Taoyuan, Taiwan; Graduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung University, Taoyuan, Taiwan; Corresponding author. Division of Rhinology, Department of Otolaryngology, Chang Gung Memorial Hospital and Chang Gung University, No. 5, Fu-Shin Street, Kweishan, Taoyuan, 333, Taiwan.Division of Rhinology, Department of Otolaryngology, Chang Gung Memorial Hospital and Chang Gung University, Taoyuan, Taiwan; Department of Otolaryngology – Head and Neck Surgery, Chang Gung Memorial Hospital and Chang Gung University, Keelung, TaiwanMolecular Infectious Disease Research Center, Chang Gung Memorial Hospital, Taoyuan, Taiwan; Division of Pediatric Infectious Diseases, Department of Pediatrics, Chang Gung Memorial Hospital and Chang Gung University, Taoyuan, TaiwanDivision of Rhinology, Department of Otolaryngology, Chang Gung Memorial Hospital and Chang Gung University, Taoyuan, TaiwanMolecular Infectious Disease Research Center, Chang Gung Memorial Hospital, Taoyuan, TaiwanBackground: Given the role of adenoid in the pathogenesis of otitis media with effusion (OME) and sleep-disordered breathing (SDB), the present study aimed to investigate the sleep quality and the impact of adenoidectomy on improvement of sleep symptoms in children with OME. Methods: Children with SDB or OME, aged 3–12 years, were prospectively enrolled before undergoing adenoidectomy in a tertiary medical center. The symptom severity of obstructive sleep apnea syndrome (OSAS) was evaluated by OSA-18 questionnaire on the day before and 6 months after surgery. Results: In total, 79 pediatric patients including 50 children with SDB and 29 children with OME were enrolled. The mean total OSA-18 score was 56.5 ± 15.1 and ten (34.5%) children experienced moderate to severe symptoms of OSAS as indicated by OSA-18 score ≥ 60 in OME group. After surgery, patients in both SDB and OME groups experienced improvement (both p < 0.001) and presented no difference in the scores of OSA-18. The proportional change in OSA-18 scores after surgery was related to pre-operative OSA-18 scores and BMI in OME patients (rs = 0.400 and 0.542, p = 0.047 and 0.008), and to pre-operative OSA-18 scores in patients with SDB (rs = 0.393, p = 0.008). Conclusion: Children with OME experienced significant symptoms of OSAS and associated impairment of quality of life. Adenoidectomy is effective in the improvement of sleep symptoms in these patients. Comprehensive assessment of sleep breathing as planning surgery for OME children is suggested.http://www.sciencedirect.com/science/article/pii/S1875957221001352adenoidectomyobstructive sleep apnea syndromeotitis media with effusionsleep-disordered breathing
spellingShingle Chien-Chia Huang
Pei-Wen Wu
Cheng-Hsun Chiu
Ta-Jen Lee
Chyi-Liang Chen
Assessment of sleep-disordered breathing in pediatric otitis media with effusion
Pediatrics and Neonatology
adenoidectomy
obstructive sleep apnea syndrome
otitis media with effusion
sleep-disordered breathing
title Assessment of sleep-disordered breathing in pediatric otitis media with effusion
title_full Assessment of sleep-disordered breathing in pediatric otitis media with effusion
title_fullStr Assessment of sleep-disordered breathing in pediatric otitis media with effusion
title_full_unstemmed Assessment of sleep-disordered breathing in pediatric otitis media with effusion
title_short Assessment of sleep-disordered breathing in pediatric otitis media with effusion
title_sort assessment of sleep disordered breathing in pediatric otitis media with effusion
topic adenoidectomy
obstructive sleep apnea syndrome
otitis media with effusion
sleep-disordered breathing
url http://www.sciencedirect.com/science/article/pii/S1875957221001352
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