Assessment of Vertebral Bone Marrow Perfusion, Fat/Water Content, and Trabecular Bone Changes Using Multimodal MRI and Micro‐CT in a Rat Model of Chronic Kidney Disease

Assessment of Vertebral Bone Marrow Perfusion, Fat/Water Content, and Trabecular Bone Changes Using Multimodal MRI and Micro‐CT in a Rat Model of Chronic Kidney Disease

ABSTRACT Background Disturbances in calcium and phosphorus homeostasis resulting from chronic kidney disease (CKD) may lead to atherosclerotic changes in blood vessels, potentially altering bone marrow perfusion. Our study aimed to investigate vertebral bone marrow perfusion using dynamic contrast–e...

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Main Authors: Guo‐Shu Huang, Shih‐Wei Chiang, Yi‐Jen Peng, Skye Hsin‐Hsien Yeh, Yu‐Juei Hsu, Yu‐Ching Chou, Heng‐Han Chang, Herng‐Sheng Lee, Ying‐Chun Liu, Chao‐Ying Wang
Format: Article
Language:English
Published: Wiley 2025-03-01
Series:JOR Spine
Subjects:
CKD
DCE‐MRI
MRS
perfusion
T2* quantification
vertebral bone marrow
Online Access:https://doi.org/10.1002/jsp2.70039
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