PolyICLC Exerts Pro- and Anti-HIV Effects on the DC-T Cell Milieu In Vitro and In Vivo.

PolyICLC Exerts Pro- and Anti-HIV Effects on the DC-T Cell Milieu In Vitro and In Vivo.

Myeloid dendritic cells (mDCs) contribute to both HIV pathogenesis and elicitation of antiviral immunity. Understanding how mDC responses to stimuli shape HIV infection outcomes will inform HIV prevention and treatment strategies. The long double-stranded RNA (dsRNA) viral mimic, polyinosinic polycy...

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Main Authors: Meropi Aravantinou, Ines Frank, Magnus Hallor, Rachel Singer, Hugo Tharinger, Jessica Kenney, Agegnehu Gettie, Brooke Grasperge, James Blanchard, Andres Salazar, Michael Piatak, Jeffrey D Lifson, Melissa Robbiani, Nina Derby
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0161730&type=printable
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