Rare clinical observation of pronounced response to immunotherapy in a patient with anaplastic thyroid cancer
Anaplastic thyroid cancer is the rarest and the most aggressive form of thyroid cancer. It comprises 1-2 % of all cases and is characterized by rapid growth. median survival of patients with this pathology is about 5 months. Clinical manifestations of the disease are rapid deformation in the neck ar...
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| Format: | Article |
| Language: | Russian |
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ABV-press
2024-06-01
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| Series: | Опухоли головы и шеи |
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| Online Access: | https://ogsh.abvpress.ru/jour/article/view/970 |
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| author | D. M. Vontlaya O. V. Stryapikhina A. A. Egorin A. V. Logvinenko R. I. Tamrazov |
| author_facet | D. M. Vontlaya O. V. Stryapikhina A. A. Egorin A. V. Logvinenko R. I. Tamrazov |
| author_sort | D. M. Vontlaya |
| collection | DOAJ |
| description | Anaplastic thyroid cancer is the rarest and the most aggressive form of thyroid cancer. It comprises 1-2 % of all cases and is characterized by rapid growth. median survival of patients with this pathology is about 5 months. Clinical manifestations of the disease are rapid deformation in the neck area, progressive respiratory distress, and dysphagia.The article describes a clinical case of a response of unresectable, BRAF-negative, PD-L1-positive (programmed death-ligand 1) anaplastic thyroid cancer to immunotherapy with pembrolizumab. |
| format | Article |
| id | doaj-art-442e4c998bc340a082940c0c66a1cbcd |
| institution | DOAJ |
| issn | 2222-1468 2411-4634 |
| language | Russian |
| publishDate | 2024-06-01 |
| publisher | ABV-press |
| record_format | Article |
| series | Опухоли головы и шеи |
| spelling | doaj-art-442e4c998bc340a082940c0c66a1cbcd2025-08-20T03:01:13ZrusABV-pressОпухоли головы и шеи2222-14682411-46342024-06-01141636910.17650/2222-1468-2024-14-1-63-69587Rare clinical observation of pronounced response to immunotherapy in a patient with anaplastic thyroid cancerD. M. Vontlaya0O. V. Stryapikhina1A. A. Egorin2A. V. Logvinenko3R. I. Tamrazov4Multidisciplinary clinical medical center “Medical city”Tyumen State Medical University, Ministry of Health of RussiaMultidisciplinary clinical medical center “Medical city”Multidisciplinary clinical medical center “Medical city”Multidisciplinary clinical medical center “Medical city”Anaplastic thyroid cancer is the rarest and the most aggressive form of thyroid cancer. It comprises 1-2 % of all cases and is characterized by rapid growth. median survival of patients with this pathology is about 5 months. Clinical manifestations of the disease are rapid deformation in the neck area, progressive respiratory distress, and dysphagia.The article describes a clinical case of a response of unresectable, BRAF-negative, PD-L1-positive (programmed death-ligand 1) anaplastic thyroid cancer to immunotherapy with pembrolizumab.https://ogsh.abvpress.ru/jour/article/view/970anaplastic thyroid cancerthyroid glandimmunotherapypembrolizumab |
| spellingShingle | D. M. Vontlaya O. V. Stryapikhina A. A. Egorin A. V. Logvinenko R. I. Tamrazov Rare clinical observation of pronounced response to immunotherapy in a patient with anaplastic thyroid cancer Опухоли головы и шеи anaplastic thyroid cancer thyroid gland immunotherapy pembrolizumab |
| title | Rare clinical observation of pronounced response to immunotherapy in a patient with anaplastic thyroid cancer |
| title_full | Rare clinical observation of pronounced response to immunotherapy in a patient with anaplastic thyroid cancer |
| title_fullStr | Rare clinical observation of pronounced response to immunotherapy in a patient with anaplastic thyroid cancer |
| title_full_unstemmed | Rare clinical observation of pronounced response to immunotherapy in a patient with anaplastic thyroid cancer |
| title_short | Rare clinical observation of pronounced response to immunotherapy in a patient with anaplastic thyroid cancer |
| title_sort | rare clinical observation of pronounced response to immunotherapy in a patient with anaplastic thyroid cancer |
| topic | anaplastic thyroid cancer thyroid gland immunotherapy pembrolizumab |
| url | https://ogsh.abvpress.ru/jour/article/view/970 |
| work_keys_str_mv | AT dmvontlaya rareclinicalobservationofpronouncedresponsetoimmunotherapyinapatientwithanaplasticthyroidcancer AT ovstryapikhina rareclinicalobservationofpronouncedresponsetoimmunotherapyinapatientwithanaplasticthyroidcancer AT aaegorin rareclinicalobservationofpronouncedresponsetoimmunotherapyinapatientwithanaplasticthyroidcancer AT avlogvinenko rareclinicalobservationofpronouncedresponsetoimmunotherapyinapatientwithanaplasticthyroidcancer AT ritamrazov rareclinicalobservationofpronouncedresponsetoimmunotherapyinapatientwithanaplasticthyroidcancer |